A Comparative Clinical Assessment of the Analgesic Efficacy of Epidural 0.2% Ropivacaine and 0.125% Bupivacaine in Postoperative Pain Relief
Authors/Creators
- 1. Senior Resident, Department of Anesthesiology, AIIMS, Patna, Bihar, India
- 2. Senior Resident, Department of General Medicine, AIIMS, Patna, Bihar, India
- 3. Associate Professor, Department of Pathology, Mahatma Gandhi Medical College, Jamshedpur, Jharkhand, India
Description
Abstract
Aim: The aim of the present study was to evaluate the analgesic efficacy of Epidural
ropivacaine 0.2% and 0.125% bupivacaine in postoperative pain relief.
Material & methods: After obtaining written informed consent, a routine data based
observational study was conducted at department of Anesthesiology, AIIMS, Patna, Bihar,
India for eight months. which involved 100 patients of ASA1, ASA2 who received Epidural
0.2% Ropivacaine and 100 patients who received Epidural 0.125%bupivacaine
postoperatively. All patients were monitored for postoperative pain by the visual analogy
scale (VAS), requirement of rescue analgesia, hemodynamic parameters and adverse effects.
Results: In the present study, there were 70% male and 30% female in Bupivacaine 0.125%
group and 65% male and 35% female in ropivacaine0.2% group. According to visual analogy
score, 2.16 score on day 1 in Bupivacaine 0.125% group and 2.40 in ropivacaine 0.2% group.
46% patients required rescue analgesia in Bupivacaine 0.125% group and 60% in ropivacaine
0.2% group. In the present study, 8% had hypotension adverse effect in Bupivacaine 0.125%
group and 2% in ropivacaine0.2% group.
Conclusion: Ropivacaine 0.2% and bupivacaine 0.125% were equally efficacious in terms of
VAS pain scores, rescue analgesic requirement, but ropivacaine had a better safety profile in
terms of less hypotension and lesser motor block.
Abstract (English)
Abstract
Aim: The aim of the present study was to evaluate the analgesic efficacy of Epidural
ropivacaine 0.2% and 0.125% bupivacaine in postoperative pain relief.
Material & methods: After obtaining written informed consent, a routine data based
observational study was conducted at department of Anesthesiology, AIIMS, Patna, Bihar,
India for eight months. which involved 100 patients of ASA1, ASA2 who received Epidural
0.2% Ropivacaine and 100 patients who received Epidural 0.125%bupivacaine
postoperatively. All patients were monitored for postoperative pain by the visual analogy
scale (VAS), requirement of rescue analgesia, hemodynamic parameters and adverse effects.
Results: In the present study, there were 70% male and 30% female in Bupivacaine 0.125%
group and 65% male and 35% female in ropivacaine0.2% group. According to visual analogy
score, 2.16 score on day 1 in Bupivacaine 0.125% group and 2.40 in ropivacaine 0.2% group.
46% patients required rescue analgesia in Bupivacaine 0.125% group and 60% in ropivacaine
0.2% group. In the present study, 8% had hypotension adverse effect in Bupivacaine 0.125%
group and 2% in ropivacaine0.2% group.
Conclusion: Ropivacaine 0.2% and bupivacaine 0.125% were equally efficacious in terms of
VAS pain scores, rescue analgesic requirement, but ropivacaine had a better safety profile in
terms of less hypotension and lesser motor block.
Files
IJCPR,Vol15,Issue5,Article10.pdf
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Additional details
Dates
- Accepted
-
2023-02-06