Published June 30, 2023 | Version v1
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A Comparative Study on Elective Laparoscopic Cholecystectomy with and Without Antibiotic Therapy

  • 1. Associate professor, Department of pharmacology, Rama Medical College and Hospital, Pilkhuwa, Uttar Pradesh, 245304
  • 2. Associate professor, Department of General surgery, Rama Medical College and Hospital, Pilkhuwa, Uttar Pradesh, 245304
  • 3. Resident, Department of General surgery, Rama Medical College and Hospital, Pilkhuwa, Uttar Pradesh, 245304

Description

Abstract
Objective: The present study was undertaken to evaluate the rate of infection in laparoscopic cholecystectomies,
and to assess the usefulness and efficacy of antibiotic prophylaxis.
Methods: A comparative study of 394 cases of Cholelithiasis who underwent elective la paroscopy in the Rama
Medical College Hospital and Research Center, Pilkhuwa, Hapur, Uttar Pradesh, during study period of January
2023 to May 2023. Patients were divided into study group and control group. All the patients were categorized
into study and control groups.
Results: The mean age of the patients in the study group was 69.2 +- 4.3 years. In the control group 1 patient
developed fever, in study group 7 patients (3.6%) developed pus discharge from port site, in which IV antibiotics
were continued in the post-operative period till the time of discharge is calculated to be 3.6%. In study group 5
patients (2.5%) had pus discharge.
Conclusions: One single dose of prophylactic intravenous antibiotic, administered at induction of anesthesia, is
sufficient to prevent postoperative infective complications in patient undergoing elective LAPC.

Abstract (English)

Abstract
Objective: The present study was undertaken to evaluate the rate of infection in laparoscopic cholecystectomies,
and to assess the usefulness and efficacy of antibiotic prophylaxis.
Methods: A comparative study of 394 cases of Cholelithiasis who underwent elective la paroscopy in the Rama
Medical College Hospital and Research Center, Pilkhuwa, Hapur, Uttar Pradesh, during study period of January
2023 to May 2023. Patients were divided into study group and control group. All the patients were categorized
into study and control groups.
Results: The mean age of the patients in the study group was 69.2 +- 4.3 years. In the control group 1 patient
developed fever, in study group 7 patients (3.6%) developed pus discharge from port site, in which IV antibiotics
were continued in the post-operative period till the time of discharge is calculated to be 3.6%. In study group 5
patients (2.5%) had pus discharge.
Conclusions: One single dose of prophylactic intravenous antibiotic, administered at induction of anesthesia, is
sufficient to prevent postoperative infective complications in patient undergoing elective LAPC.

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Additional details

Dates

Accepted
2023-05-24