Leiomyomas of the Urinary Bladder: An Analytical Study
Authors/Creators
- 1. Additional Professor, Department of Urology, Government Medical College, Trivandrum, Kerala, India
- 2. Senior Resident, Department of Urology, Government Medical College, Trivandrum, Kerala, India
Description
Background: Benign bladder tumours especially bladder leiomyomas are unusual tumours with significant clinical overlap with malignant bladder tumours. Their diagnosis often requires trans-urethral biopsy and histopathological analysis. However, follow-up protocols for benign bladder tumours are different from those for urothelial carcinoma. Methods: The retrospective descriptive study was conducted in a tertiary care centre, with data collected from a period between December 2017 and December 2020. All patients who were diagnosed and treated for leiomyomas and other benign tumours of the urinary bladder during the study period were reviewed retrospectively. Results: During the 3-year study period, 15 patients had been diagnosed with benign tumours of the urinary bladder. The majority of patients presented with LUTS (80%). Haematuria was also present in a significant number of patients as well (53.3%). The most common tumour was leiomyoma of the urinary bladder, with 6 cases. Conclusions: Distinction between benign and malignant bladder tumours is important as follow-up protocols differ between these entities. Definitive diagnosis required a transurethral biopsy from the tumour followed by histopathological analysis.
Abstract (English)
Background: Benign bladder tumours especially bladder leiomyomas are unusual tumours with significant clinical overlap with malignant bladder tumours. Their diagnosis often requires trans-urethral biopsy and histopathological analysis. However, follow-up protocols for benign bladder tumours are different from those for urothelial carcinoma. Methods: The retrospective descriptive study was conducted in a tertiary care centre, with data collected from a period between December 2017 and December 2020. All patients who were diagnosed and treated for leiomyomas and other benign tumours of the urinary bladder during the study period were reviewed retrospectively. Results: During the 3-year study period, 15 patients had been diagnosed with benign tumours of the urinary bladder. The majority of patients presented with LUTS (80%). Haematuria was also present in a significant number of patients as well (53.3%). The most common tumour was leiomyoma of the urinary bladder, with 6 cases. Conclusions: Distinction between benign and malignant bladder tumours is important as follow-up protocols differ between these entities. Definitive diagnosis required a transurethral biopsy from the tumour followed by histopathological analysis.
Files
IJPCR,Vol15,Issue5,Article233.pdf
Files
(1.4 MB)
| Name | Size | Download all |
|---|---|---|
|
md5:d625cf941eeec2ae14789920914220e7
|
1.4 MB | Preview Download |
Additional details
Dates
- Accepted
-
2023-05-24
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue5,Article233.pdf
- Development Status
- Active
References
- 1. Bray F, Ren JS, Masuyer E, Ferlay J. Global estimates of cancer prevalence for 27 sites in the adult population in 2008. Int J Cancer. 2013 Mar 1;132(5):1133–45. 2. Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015 Mar 1;136(5):E359-386. 3. Knoll LD, Segura JW, Scheithauer BW. Leiomyoma of the bladder. J Urol. 1986 Oct;136(4):906–8. 4. Kabalin JN, Freiha FS, Niebel JD. Leiomyoma of bladder. Report of 2 cases and demonstration of ultrasonic appearance. Urology. 1990 Mar; 35(3): 210–2. 5. Cornella JL, Larson TR, Lee RA, Magrina JF, Kammerer-Doak D. Leiomyoma of the female urethra andbladder: report of twenty-three patients and review of the literature. Am J Obstet Gynecol. 1997 Jun; 176(6): 1278–85. 6. Goluboff ET, O'Toole K, Sawczuk IS. Leiomyoma of bladder: report of case and review of literature. Urology. 1994 Feb;43(2):238–41. 7. Teran AZ, Gambrell RD. Leiomyoma of the bladder: case report and review of the literature. Int J Fertil. 1989 Aug;34(4):289–92. 8. Saunders SE, Conjeski JM, Zaslau S, Williams J, Kandzari SJ. Leiomyoma of the urinary bladder presenting as urinary retention in the female. Can J Urol. 2009 Aug;16(4):4762–4. 9. Katz RB, Waldbaum RS. Benign mesothelial tumor of bladder. Urology. 1975 Feb;5(2):236–8. 10. Kutzmann AA. Leiomyoma of the Urinary Bladder1. J Urol. 1937 Jan;37(1):117–32. 11. Melicow MM. Tumors of the Urinary Bladder: a Clinicopathological Analysis of Over 2500 Specimens and Biopsies. J Urol. 1955 Oct;74(4):498– 521. 12. Wenz W, Sommerkamp H, Dinkel E. Leiomyoma of the bladder. Urol Radiol. 1986;8(2):114–7. 13. Silva-Ramos M, Massó P, Versos R, Soares J, Pimenta A. [Leiomyoma of the bladder. Analysis of a collection of 90 cases]. Actas Urol Esp. 2003 Sep;27(8):581–6. 14. Fernández Fernández A, Mayayo Dehesa T. Leiomyoma of the urinary bladder floor: diagnosis by transvaginal ultrasound. Urol Int. 1992;48(1):99– 101. 15. Khater N, Sakr G. Bladder leiomyoma: Presentation, evaluation and treatment. Arab J Urol. 2013 Mar;11(1):54–61. 16. Ho L, Jones E, Kavanagh A. Benign inverted papilloma at bladder neck causing acute urinary retention. J Surg Case Rep. 2018 Jun 15;2018(6):rjy125. 17. Witjes JA, van Balken MR, van de Kaa CA. The prognostic value of a primary inverted papilloma of the urinary tract. J Urol. 1997 Oct;158(4):1500–5. 18. Sweeney MK, Rais-Bahrami S, Gordetsky J. Inverted urothelial papilloma: A review of diagnostic pitfalls and clinical management. Can Urol Assoc J. 2017;11(1–2):66–9. 19. Inverted papilloma of urinary bladder: is long-term cystoscopic surveillance needed? A single center's experience. [Internet]. [cited 2022 Oct 2]. Available from: https://reference.medscape.com/medlin e/abstract/16904447 20. Semins MJ, Schoenberg MP. A case of florid cystitis glandularis. Nat Clin Pract Urol. 2007 Jun;4(6):341–5. 21. Radswiki T. Cystitis cystica | Radiology Reference Article | Radiopaedia.org [Internet]. Radiopaedia. [cited 2022 Oct 2]. Available from: https://radiopaedia.org/articles/cystitiscystica 22. Bullock PS, Thoni DE, Murphy WM. The significance of colonic mucosa (intestinal metaplasia) involving the urinary tract. Cancer. 1987 Jun 15; 59(12):2086–90. 23. Jacobs LB, Brooks JD, Epstein JI. Differentiation of colonic metaplasia from adenocarcinoma of urinary bladder. Hum Pathol. 1997 Oct; 28(10): 1152–7. 24. Young RH, Bostwick DG. Florid cystitis glandularis of intestinal type with mucin extravasation: a mimic of adenocarcinoma. Am J Surg Pathol. 1996 Dec;20(12):1462–8. 25. Bryan RT, Nicholls JH, Harrison RF, Jankowski JA, Wallace DMA. The role of beta-catenin signaling in the malignant potential of cystitis glandularis. J Urol. 2003 Nov; 170(5): 1892–6. 26. Mitre AI, Silveira CAP, Leite KRM, Piovesan AC. Glandular cystitis: a rare benign condition presenting as a pseudo-tumor of the bladder. Clin Sao Paulo Braz. 2007 Feb;62(1):93–4.27. Corica FA, Husmann DA, Churchill BM, Young RH, Pacelli A, LopezBeltran A, et al. Intestinal metaplasia is not a strong risk factor for bladder cancer: study of 53 cases with longterm follow-up. Urology. 1997 Sep; 50(3):427–31.