Published July 1, 2024 | Version v1
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Determination of the structural parameters of Repaglinide in tablet: an antidiabetic drug, using Spectroscopic methods

  • 1. Libyan Association for Pharmacists

Description

Abstract: The spectroscopy area provides molecular-level information about an anti-diabetic drug through qualitative and quantitative analysis, Repaglinide is an antidiabetic medication in the meglitinide class that is used to treat type II diabetes mellitus. The objective of this work was to characterize Repaglinide by using UV spectroscopy (UV), nuclear magnetic resonance (NMR), and infrared spectrometry (FTIR).  The UV results showed that the maximum absorption was at 208, 243, and 285 nm. The IR spectra obtained are consistent with those described in the literature. The NMR-1H spectra revealed information about the various hydrogen and carbon atoms in the molecule as well as their chemical surroundings. The provided methods were successfully employed to control a drug with great accuracy and precision.

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