Study to Determine the Effect of Phototherapy on Serum Magnesium Level in Term Neonates with Hyperbilirubinemia: An Observational Study
Authors/Creators
- 1. Senior Consultant, Department of Neonatology, Yashvi Children Hospital, Patna, Bihar, India
- 2. Senior Resident, Department of Pathology, Bhagwan Mahavir Institute of Medical Sciences, Pawapuri, Nalanda, Bihar, India
- 3. Assistant Professor, Department of Microbiology, RDJM Medical College and Hospital , Turki, Muzaffarpur, Bihar, India
Description
Abstract
Aim: The aim of the present study was to determine the effect of phototherapy on serum magnesium level in term
neonates with hyperbilirubinemia.
Material & methods: A prospective hospital‑based comparative study was conducted on 200 eligible neonates
admitted in the Department of Neonatology, receiving phototherapy for the period of one year. informed consent
was obtained from the parents of the selected neonates. This study included 200 full‑term neonates who were
subjected to phototherapy for treating neonatal hyperbilirubinemia according to the guidelines of the American
Academy of Pediatrics.
Results: Our study included 200 full‑term neonates with jaundice who received phototherapy for treating neonatal
indirect hyperbilirubinemia, comprising 130 (65%) males, and 70 (35%) females, with the mean gestational age
of 37 ± 0.8 weeks and mean postnatal age of 5.4 ± 1.3 days. There were 68 (34%) neonates delivered by normal
vaginal delivery and 132 (66%) neonates delivered by cesarean section. Mean birth weight was 3.2 kg. Subjects
have a mean intrauterine age of 38.45 weeks and a jaundice onset age of 3.67 days. The mean difference of
jaundice onset age, intrauterine age, admission weight and mother’s age were not significant. Serum total
magnesium level in single and double phototherapy decreases after treatment, but this decrease is significant only
in the double phototherapy group (P = 0.032). In the intensive group, this parameter has slightly increased, which
is not statistically significant (P = 0.575). The serum total magnesium level and its changes were reported in three
groups before and after phototherapy. The serum magnesium level in new borns before treatment was normal in
all three treatment groups. The status of each patient showed that single, double, and intensive phototherapy
groups have magnesium content of more than 2.2 mg/dl, respectively.
Conclusion: In the present study, the serum magnesium level showed a significant reduction only in the double
phototherapy method and remained in the normal range in the other two groups. On the other hand, in all three
treatment groups, the level of serum magnesium before the treatment was normal and did not increase
significantly
Abstract (English)
Abstract
Aim: The aim of the present study was to determine the effect of phototherapy on serum magnesium level in term
neonates with hyperbilirubinemia.
Material & methods: A prospective hospital‑based comparative study was conducted on 200 eligible neonates
admitted in the Department of Neonatology, receiving phototherapy for the period of one year. informed consent
was obtained from the parents of the selected neonates. This study included 200 full‑term neonates who were
subjected to phototherapy for treating neonatal hyperbilirubinemia according to the guidelines of the American
Academy of Pediatrics.
Results: Our study included 200 full‑term neonates with jaundice who received phototherapy for treating neonatal
indirect hyperbilirubinemia, comprising 130 (65%) males, and 70 (35%) females, with the mean gestational age
of 37 ± 0.8 weeks and mean postnatal age of 5.4 ± 1.3 days. There were 68 (34%) neonates delivered by normal
vaginal delivery and 132 (66%) neonates delivered by cesarean section. Mean birth weight was 3.2 kg. Subjects
have a mean intrauterine age of 38.45 weeks and a jaundice onset age of 3.67 days. The mean difference of
jaundice onset age, intrauterine age, admission weight and mother’s age were not significant. Serum total
magnesium level in single and double phototherapy decreases after treatment, but this decrease is significant only
in the double phototherapy group (P = 0.032). In the intensive group, this parameter has slightly increased, which
is not statistically significant (P = 0.575). The serum total magnesium level and its changes were reported in three
groups before and after phototherapy. The serum magnesium level in new borns before treatment was normal in
all three treatment groups. The status of each patient showed that single, double, and intensive phototherapy
groups have magnesium content of more than 2.2 mg/dl, respectively.
Conclusion: In the present study, the serum magnesium level showed a significant reduction only in the double
phototherapy method and remained in the normal range in the other two groups. On the other hand, in all three
treatment groups, the level of serum magnesium before the treatment was normal and did not increase
significantly
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Additional details
Dates
- Accepted
-
2023-08-23