A Comparative Study of Intravenous Propofol and Inhalational Sevoflurane for Preoperative Induction
Authors/Creators
- 1. Assistant Professor, Department of Anesthesiology, Motilal Nehru Medical College, Prayagraj, UP, India
- 2. Associate Professor, Department of Anesthesiology, SS Medical College, Rewa, MP, India
- 3. Assistant Professor, Department of Anesthesiology, MGMMC and MY Hospital, Indore, MP, India
- 4. Assistant Professor, Department of Anesthesiology, United Institute of Medical Sciences, Prayagraj, UP, India
Description
Abstract
Background and Objectives: Propofol is commonly used for anesthesia induction, while Sevoflurane is
favored for pediatric inhalational induction and adult needle-phobic patients. This study aims to compare
Propofol and Sevoflurane induction agents and their impact on intubation conditions, particularly in relation to
Sevoflurane's interaction with vecuronium, a non-depolarizing muscle relaxant.
Methods: ASA Grade I and II patients (20-65 years) undergoing surgeries were randomized into two groups.
Group P received Propofol induction, and Group S received Sevoflurane induction using vital capacity breath
technique (8% Sevoflurane).
Results: Propofol induced more significant blood pressure reduction, though induction time was slightly
shorter. Sevoflurane heightened vecuronium's effects. One Sevoflurane subject experienced laryngospasm
(excluded). Four Propofol patients had injection pain. Both groups had instances of groaning, while Sevoflurane
group showed induction-related coughing.
Conclusion: Propofol and Sevoflurane exhibit similar induction speed. Sevoflurane enhances non-depolarizing
muscle relaxant effects during induction, making it preferable for patients intolerant to brief blood pressure
decline.
Abstract (English)
Abstract
Background and Objectives: Propofol is commonly used for anesthesia induction, while Sevoflurane is
favored for pediatric inhalational induction and adult needle-phobic patients. This study aims to compare
Propofol and Sevoflurane induction agents and their impact on intubation conditions, particularly in relation to
Sevoflurane's interaction with vecuronium, a non-depolarizing muscle relaxant.
Methods: ASA Grade I and II patients (20-65 years) undergoing surgeries were randomized into two groups.
Group P received Propofol induction, and Group S received Sevoflurane induction using vital capacity breath
technique (8% Sevoflurane).
Results: Propofol induced more significant blood pressure reduction, though induction time was slightly
shorter. Sevoflurane heightened vecuronium's effects. One Sevoflurane subject experienced laryngospasm
(excluded). Four Propofol patients had injection pain. Both groups had instances of groaning, while Sevoflurane
group showed induction-related coughing.
Conclusion: Propofol and Sevoflurane exhibit similar induction speed. Sevoflurane enhances non-depolarizing
muscle relaxant effects during induction, making it preferable for patients intolerant to brief blood pressure
decline.
Files
IJCPR,Vol15,Issue8,Article72.pdf
Files
(298.3 kB)
| Name | Size | Download all |
|---|---|---|
|
md5:661eef3bf1fb17fd8a9a576a3cc0eaa7
|
298.3 kB | Preview Download |
Additional details
Dates
- Accepted
-
2023-07-30