Published May 31, 2023 | Version https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue5,Article14.pdf

The Bethesda System of Reporting Thyroid Cytopathology: A Hospital Based Study of Eastern UP

  • 1. Postgraduate Resident, Department of Pathology, Heritage Institute of Medical Sciences, Varanasi
  • 2. Associate Professor, Department of Pathology, Heritage Institute of Medical Sciences, Varanasi
  • 3. Professor, Department of Pathology, Heritage Institute of Medical Sciences, Varanasi

Description

Background: Fine needle aspiration cytology is a well-established first line diagnostic tool for the evaluation of palpable thyroid swellings. It is one of the diagnostic investigations for the Evaluation of solitary thyroid nodule (distinguish neoplastic from non -neoplastic), Evaluation of diffuse thyroid lesions (distinguish inflammatory/ autoimmune from nodular goiter), Confirmation and categorisation of clinically obvious thyroid malignancy. Thyroid FNAC is the most accurate and cost-effective tool for guiding the clinical management of patients with thyroid nodules. The role of cytology in thyroid swellings is important for the pre-operative diagnosis of benign or malignant lesions. Aims: To assess the thyroid swelling by fine needle aspiration cytology and classify the FNAC findings according to the Bethesda system of reporting thyroid cytopathology 2017 at a tertiary care hospital. Materials & Methods: It is an observational study done from January 2019 to November 2022. FNAC was performed in 92 cases. Smears stained with Giemsa, Haematoxylin and Eosin and Papanicolaou stain. Result: In present study commonest indication of FNAC was swelling in neck. Among 92 cases, non-neoplastic category II lesions were the major proportion constituting 78.26%%, category I unsatisfactory smears were 4.34%%, category III 3.26%%, next highest percentage of cases were in category IV with 8.69%, category V 4.34% and category VI had 1.08% of cases. Majority of the patients (78.26%) presented with Category II lesions. Among the benign lesion goiter was the most common lesion (64.12%). Nodular goiter formed maximum cases (57.60%) rest were of (6.52%). Next common lesions was thyroiditis in which lymphocytic thyroiditis was common (8.69%) followed by Hashimoto thyroiditis (3.26%) and Dequervain’s thyroiditis (2.17%). Conclusion: In conclusion the present study shows that TBSRTC helps standardize cytology reports thereby improving the quality of reporting, reducing the diagnostic in accuracies and bringing about an interlaboratory agreement on an objective basis. Furthermore it improves the communication between cytopathologists and clinicians, helping them to triage the patient for the appropriate line of management.

 

 

 

Abstract (English)

Background: Fine needle aspiration cytology is a well-established first line diagnostic tool for the evaluation of palpable thyroid swellings. It is one of the diagnostic investigations for the Evaluation of solitary thyroid nodule (distinguish neoplastic from non -neoplastic), Evaluation of diffuse thyroid lesions (distinguish inflammatory/ autoimmune from nodular goiter), Confirmation and categorisation of clinically obvious thyroid malignancy. Thyroid FNAC is the most accurate and cost-effective tool for guiding the clinical management of patients with thyroid nodules. The role of cytology in thyroid swellings is important for the pre-operative diagnosis of benign or malignant lesions. Aims: To assess the thyroid swelling by fine needle aspiration cytology and classify the FNAC findings according to the Bethesda system of reporting thyroid cytopathology 2017 at a tertiary care hospital. Materials & Methods: It is an observational study done from January 2019 to November 2022. FNAC was performed in 92 cases. Smears stained with Giemsa, Haematoxylin and Eosin and Papanicolaou stain. Result: In present study commonest indication of FNAC was swelling in neck. Among 92 cases, non-neoplastic category II lesions were the major proportion constituting 78.26%%, category I unsatisfactory smears were 4.34%%, category III 3.26%%, next highest percentage of cases were in category IV with 8.69%, category V 4.34% and category VI had 1.08% of cases. Majority of the patients (78.26%) presented with Category II lesions. Among the benign lesion goiter was the most common lesion (64.12%). Nodular goiter formed maximum cases (57.60%) rest were of (6.52%). Next common lesions was thyroiditis in which lymphocytic thyroiditis was common (8.69%) followed by Hashimoto thyroiditis (3.26%) and Dequervain’s thyroiditis (2.17%). Conclusion: In conclusion the present study shows that TBSRTC helps standardize cytology reports thereby improving the quality of reporting, reducing the diagnostic in accuracies and bringing about an interlaboratory agreement on an objective basis. Furthermore it improves the communication between cytopathologists and clinicians, helping them to triage the patient for the appropriate line of management.

 

 

 

Files

IJPCR,Vol15,Issue5,Article14.pdf

Files (1.3 MB)

Name Size Download all
md5:40c6308c1fe9eaa895037695b7f7fae7
1.3 MB Preview Download

Additional details

Dates

Accepted
2023-05-04

References

  • 1. Gupta M, Gupta S, Gupta VB. Correlation of fine needle aspiration cytology with histopathology in the diagnosis of solitary thyroid nodule. J Thyroid Res. 2010 Apr;2010:1 – 5. 2. Cibas ES, Ali SZ. The Bethesda system for reporting thyroid cytopathology. Am J Clin Pathol. 2009 Nov;132(5):658-65. 3. Ramteke DJ, Mulay PS. Cytohistopathological correlation of thyroid lesions. Int J Res Med Sci. 2017; 5(4): 1425-9. 4. Ergete W, Abebe D. Discordance rate between thyroid fine needle aspiration cytology and histopathologic diagnosis. Ethiop J Health Dev. 2002;16(2):227-31. 5. Mehra P, Verma AK. Thyroid cytopathology reporting by the Bethesda system: a two-year prospective study in an academic institution. Patholog Res Int. 2015 Jan; 2015:1-15. 6. Tagore S, Jyaprakash HT, Sasidharan A, Nagaraj T, Santosh HN, Balraj L. Cytological study of thyroid lesions by fine-needle aspiration cytology.J Med Radiol Pathol Surg. 2016;2:12-15. 7. Dr Priya P Kartha et al JMSCR. July 2017;05(07): 25615. 8. Gopal MR, Rao KJ, Sai AR. Clinicopathological study of thyroid lesions overa period of one year in a tertiary care centre.J. Evolution Med. Dent. Sci. 2018; 7(31):3513-3517. 9. Athavale VS, Thakkar SM, Gope DD, Tulsian AR, Kumar SB, Gogineni JC. A clinicopathological study of multinodular goitre. Int Surg J. 2019; 6:892-7. 10. Bakiarathana Anand, Anita Ramdas, Marie Moses Ambroise, and Nirmal P. Kumar The Bethesda system for reporting thyroid cytopathology: A Cytohistological study Journal of thyroid research. 2020; Article ID 8095378,8 Pages. 11. Patel A, Patel V. Cytopathological study of thyroid lesions and its correlation with histopathology in a tertiary care centre of Gujarat – A retrospective study. IP J Diagn Pathol Oncol. 2021;6(2):109-114. 12. Shital Sameer Dharrao and Suresh V Mahajan Fine Needle Aspiration Cytological Study of Various Thyroid Lesions and its Clinical Correlation in a Tertiary Health Care Centre - A Prospective Study MVP Journal of Medical Sciences. July-December 2017; 4(2):152-155. 13. Tazeen Jeelani, Danish Rafiq, Wajahatun Nazir, Yaavar Shafi, Naheena Bashir, Anu Charak, Nusrat Bashir, Shujat Ahamad, Barqui Afaq, Showkat Ahamad, K. M Baba Histopathological and cytological correlation of thyroid nodule with emphasis on Bethesda system of reporting thyroid cytology A 7 year study. International Journal of contemporary medical research. January 2018;5(1). 14. Akhila Sekhar, Inamdae S.S, V.D. Dombale, Prabhu M.H. Fine Needle Aspiration Cytology Study of Thyroid Lesions – A 2 year prospective study in a Tertiary centre. International Journal of Pharmaceutical and Biological Science Archive. 2015;3(1):15-19. 15. Dr. Neha Mukesh Goel, Miss Madhura Nitin Surve. Cytological Evaluation of Thyroid Lesions and its correlation with Histopathology: A study in a Rural tertiary care Hospital, Konkan belt of Maharashtra, India.Journal of Dental and Medical Sciences. October. 2018; 17(10); Ver.6:01-14. 16. Munavarah S A, Bhosle A A, Jeybalan N Fine Needle aspiration cytopathology of thyroid lesionsreporting as per guidelines of recent Bethesda system at a tertiary care teaching medical college & hospital. February-2019; 8(2). 17. I. V. Renuka, G. Saila Bala, C. Aparna, Ramana Kumari, K. Sumalatha. The Bethesda system for reporting Thyroid cytopathology: Interpretation and Guidelines in surgical Treatment Indian J Otolaryngol Head Neck Surg. OctoberDecember 2012; 64(4):305-311. 18. Rajesh Singh Laishram, Tlangte Zothanmawii, Zothansung Joute, Padi Yasung, Kaushik Debnath The Bethesda system of reporting thyroid fine needle aspirates: A 2 year cytologic study in a tertiary care institute. Journal of Medical society. January-April 2017;31(1). 19. Alshaikh S, Harb Z, Aljufairi E, Almahari SA. Classification of thyroid fine-needle aspiration cytology into Bethesda categories: An institutional experience and review of the literature. Cyto Journal. 2018; 15:4. 20. Krishna Chaitanya V, Prudhvinath Kurakula. Study of clinicopathological profile of solitary nodule in thyroid at a tertiary hospital. MedPulse International Journal of Surgery. March 2021; 17(3): 64-67.