A Hospital Based Observational Assessment of the Histopathology of Benign Proliferative Breast Lesions in Peritumoral Area of Carcinoma Breast

Description

Abstract (English)

Abstract
Aim: The aim of the study was to determine histopathological features of different subtypes of carcinoma breast
and correlate with the presence of proliferative lesions of breast in peritumoral area.
Methods: This Observational study was conducted for a period of 1 year at department of Pathology,
Darbhanga Medical College and Hospital, Darbhanga, Bihar, India and A total of 100 cases that satisfied the
inclusion criteria were included in this study. Specimens were received in 10% Formalin. Clinical details, gross
findings including tumor size were noted.
Results: Age group of patients included in the study ranges between 32 to 76 years with a mean age of 54 years.
Majority of the patients belonged to 51 to 60 years seen in 35 (35%) cases. 44 (44%) cases belonged to
postmenopausal age group, 37 (37%) and 17(20%) belonged to perimenopausal and premenopausal age group
respectively. In the present study, 55 (55%) of tumors were located at the right side, 45 (45%) at the left side
breast. None of the patients had bilateral carcinoma. Of the 100 cases included in the present study 82 (82%)
were Invasive Ductal Carcinoma of No Special Type (IDC NST). Most common findings in peritumoral area of
breast were non proliferative epithelial lesions 53 (53%).
Conclusion: The present study concluded that non-proliferative breast lesions were the most predominant
histological lesion in peritumoral area. Histopathological examination of peritumoral area in mastectomy
specimens is a simple and valuable method that helps to stratify the risk of carcinoma in contralateral breast.