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Published June 26, 2024 | Version v1.4.0
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az7jh2/SDePER: SDePER v1.4.0

Authors/Creators

Description

Updates:

  • Added single cell augmentation feature for scRNA-seq reference data.

  • Implemented failure steps for handling irregular $\theta$ values after optimization.

  • Added support for transferring cell type proportions based on PCA or UMAP embeddings of latent space, or directly on the original latent space in cell type proportion prediction using CVAE.

  • Introduced caching in GLRM to accelerate computations by storing calculated likelihood values, reducing duplicate calculations. Note: This feature is disabled by default due to potential optimization failures caused by unknown reasons (#5).

Bug Fixes:

  • Resolved issue with spot name inconsistencies when spots are filtered out if cell type proportions predicted by CVAE were used for $\theta$ initialization in GLRM modeling.

  • Fixed bug causing errors when plotting CVAE loss during training in the absence of validation data.

Files

az7jh2/SDePER-v1.4.0.zip

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Additional details

Related works

Is supplement to
Software: https://github.com/az7jh2/SDePER/tree/v1.4.0 (URL)