az7jh2/SDePER: SDePER v1.4.0
Authors/Creators
Description
Updates:
Added single cell augmentation feature for scRNA-seq reference data.
Implemented failure steps for handling irregular $
\theta$ values after optimization.Added support for transferring cell type proportions based on PCA or UMAP embeddings of latent space, or directly on the original latent space in cell type proportion prediction using CVAE.
Introduced caching in GLRM to accelerate computations by storing calculated likelihood values, reducing duplicate calculations. Note: This feature is disabled by default due to potential optimization failures caused by unknown reasons (#5).
Bug Fixes:
Resolved issue with spot name inconsistencies when spots are filtered out if cell type proportions predicted by CVAE were used for $
\theta$ initialization in GLRM modeling.Fixed bug causing errors when plotting CVAE loss during training in the absence of validation data.
Files
az7jh2/SDePER-v1.4.0.zip
Files
(109.1 kB)
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Additional details
Related works
- Is supplement to
- Software: https://github.com/az7jh2/SDePER/tree/v1.4.0 (URL)