A Study on Resistance to Systemic Antifungal Drugs in Dermatophytosis
Authors/Creators
- 1. Professor & Head of the Department, Department of Microbiology, NRI Institute of Medical Sciences, Visakhapatnam
- 2. Professor, Department of Pathology, NRI Institute of Medical Sciences, Visakhapatnam
- 3. Associate Professor, Department of Pathology, NRI Institute of Medical Sciences, Visakhapatnam
- 4. Senior Resident, Department of Microbiology, NRI Institute of Medical Sciences, Visakhapatnam
- 5. Assistant Professor, Department of Pathology, NRI Institute of Medical Sciences, Visakhapatnam
Description
Dermatophytosis is a common fungal infection of the skin caused by dermatophytes. This study aimed to identify the species of organisms causing dermatophytosis and evaluate their susceptibility to commonly used antifungal medications. A cross-sectional descriptive study was conducted on 100 patients diagnosed with superficial dermatophytosis. Data on demographics, disease history, and clinical manifestations were collected. Samples were obtained from lesions and hair, and microscopic examination and culture were performed. Trichophyton, Mentagrophytes and Trichophyton rubrum were the most commonly isolated species. Tinea corporis was the predominant clinical type. Antifungal susceptibility testing revealed Terbinafine to have the lowest minimum inhibitory concentration (MIC) among the tested drugs. The study emphasizes the importance of accurate identification and susceptibility testing to guide effective treatment of dermatophytosis.
Abstract (English)
Dermatophytosis is a common fungal infection of the skin caused by dermatophytes. This study aimed to identify the species of organisms causing dermatophytosis and evaluate their susceptibility to commonly used antifungal medications. A cross-sectional descriptive study was conducted on 100 patients diagnosed with superficial dermatophytosis. Data on demographics, disease history, and clinical manifestations were collected. Samples were obtained from lesions and hair, and microscopic examination and culture were performed. Trichophyton, Mentagrophytes and Trichophyton rubrum were the most commonly isolated species. Tinea corporis was the predominant clinical type. Antifungal susceptibility testing revealed Terbinafine to have the lowest minimum inhibitory concentration (MIC) among the tested drugs. The study emphasizes the importance of accurate identification and susceptibility testing to guide effective treatment of dermatophytosis.
Files
IJPCR,Vol15,Issue6,Article186.pdf
Files
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Additional details
Dates
- Accepted
-
2023-06-19
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue6,Article186.pdf
- Development Status
- Active
References
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