Published March 30, 2022 | Version http://impactfactor.org/PDF/IJTPR/12/IJTPR,Vol12,Issue3,Article2.pdf

Autopsy Study of Death Due to Inhalation Poisons (Asphyxiants): A One Year Retrospective Study Done at Victoria Hospital, Bangalore

  • 1. Associate professor, Department of Forensic medicine and Toxicology, Bangalore medical college & research institute, Bangalore
  • 2. Senior resident, Department of Forensic medicine and Toxicology, Bangalore medical college & research institute, Bangalore
  • 3. Post graduate student, Department of Forensic medicine and Toxicology, Bangalore medical college & research institute, Bangalore

Description

A poison may be defined as any substance which, if introduced into or brought in contact with a live body, produces disease, deformity, or death.1 Routes may be ingestion, injection, inhalation, or entry through any other orifices of the body. Poisoning may occur accidentally or intentionally as in suicide or homicide. Although poisoning by inhalation makes up the least common way of poisoning, most end up in sudden death. In urban setups like Central Bangalore, inhalational poisons are mainly due to occupational poisoning as seen in industries, sewage workers and in ill ventilated places (irrespirable gases). In both scenarios, most of the cases are lethal which makes this study important. A 12-month study was carried out at Victoria hospital attached to Bangalore Medical College & Research Institute. A total of 2,414 autopsies were done from July 2020 to June 2021, out of which 296 (12.26%) were poisoning cases and. Out of these 18 (6.08%) were due to inhalation of poisonous gases. In majority of cases, Forensic science laboratory reports revealed presence of poisonous substance / irrespirable gases with majority of the gender of the deceased being males. Most of the victims had died on spot or within short intervals after exposure, which points to sudden and high fatality characteristics of inhalation poisons. Maximum number of deaths occurred at workplace followed by accidental inhalation at place of residence.

Abstract (English)

A poison may be defined as any substance which, if introduced into or brought in contact with a live body, produces disease, deformity, or death.1 Routes may be ingestion, injection, inhalation, or entry through any other orifices of the body. Poisoning may occur accidentally or intentionally as in suicide or homicide. Although poisoning by inhalation makes up the least common way of poisoning, most end up in sudden death. In urban setups like Central Bangalore, inhalational poisons are mainly due to occupational poisoning as seen in industries, sewage workers and in ill ventilated places (irrespirable gases). In both scenarios, most of the cases are lethal which makes this study important. A 12-month study was carried out at Victoria hospital attached to Bangalore Medical College & Research Institute. A total of 2,414 autopsies were done from July 2020 to June 2021, out of which 296 (12.26%) were poisoning cases and. Out of these 18 (6.08%) were due to inhalation of poisonous gases. In majority of cases, Forensic science laboratory reports revealed presence of poisonous substance / irrespirable gases with majority of the gender of the deceased being males. Most of the victims had died on spot or within short intervals after exposure, which points to sudden and high fatality characteristics of inhalation poisons. Maximum number of deaths occurred at workplace followed by accidental inhalation at place of residence.

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Dates

Accepted
2022-02-20

References

  • 1. P V Guharaj, Sudhir K Gupta. Textbook of Forensic medicine & Toxicology, 3rd edition. 2019. P.504 - 531. 2. V V Pillay. Comprehensive Medical toxicology, 5th edition. P. 393 – 445. 3. Flury KE, Dines DE, Rodante JR. Airway obstruction due to inhalation of Ammonia. Mayo Clin Proc 1983; 59: P. 389 – 393. 4. Gardini C, Castoldi AF, Candusa SM, Locatelli C. Carbon Monoxide Cardio toxicity. Journal of Toxicol Clin Toxicol. 2001; 39(1) P.35 – 44. 5. Dermistan A. Carbon Monoxide poisoning and the eye. J Roy Society medicine 2001; 94: P.425 – 426. 6. Yiqun Y, Xne L, Yanrang X, et al. Impairment of cardiac function by acute CO poisoning. Chinese medical science journal. 2002; 17: P.253. 7. Weaver LK. Clinical practice. CO poisoning. N Engl J Med 2009. 360: 1217 – 1225. 8. Noor Kool DM, Kirkpatrick JN. Treatment of Acute CO poisoning with Hyperbaric Oxygen. A review of 115 cases. Ann emergency Medi.1985; 14: 1168 – 71. 9. Nadesar K. Carbon Monoxide poisoning from car exhaust fumes. American Journal of Forensic medicine and Toxicology. 1998; 15: 53 – 56. 10. Venkataraghava S. Devadass PK, Gas geysers; serial killers causing death due to Carbon monoxide poisoning Journal of Indian society of Toxicology. 2007; 3(2): 8 – 10. 11. Way JL Cyanide intoxication, its mechanism of antagonism. Annu Rev Pharmacol Toxicol 1984; 24: 451 – 481. 12. Ballantyne B, Marrs TC, Post-mortem features and criteria for diagnosis of acute lethal cyanide poisoning in clinical and experimental toxicology and cyanides. 1987; Wright Bristol, P. 217 – 241. 13. Reiffenstein RJ, Hillbert WC, Roth SH, Toxicology of hydrogen sulphide. Annual Rev Pharmacol Toxicol 1992; 32: 109 – 134. 14. Knight LD, Presnell SE. Death by sewer gas; Case report of a double fatality. Ann J Forensic Patho 2005; 26: 181 – 185. 15. Langfold NJ, Carbon dioxide poisoning. Toxicol Rev: 2005; 24(4): 229 – 235.