Study of Diagnosis of Malaria Using Rapid Diagnostic Test (RDT) in Children
Authors/Creators
- 1. Senior Resident, Department of Pediatrics, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar
- 2. Assistant Professor, Department of Pediatrics, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar
Description
Background: In tropical nations, malaria is still a public health concern. In these nations, clinical evaluation, microscopy, the gold standard and more recently, rapid diagnostic tests (RDTs) are the mainstays of diagnosis. The purpose of this study is to evaluate the quick diagnostic test’s diagnostic accuracy for detecting malaria in children who have a clinical suspicion of having the disease. They used microscopy as the gold standard. Methods: This six-month cross-sectional and observational study was carried out at the SKMCH in Muzaffarpur, Bihar, from November 2022 to April 2023. In this study, 70 patients of both sexes with a clinical suspicion of malaria and ages up to 12 years were enrolled. Age, sexual orientation, and symptoms were noted in great detail. A quick diagnostic test was run, and the results were compared to microscopic analysis. Microscopy was regarded as the ultimate test. The Rapid Diagnostic Test’s sensitivity, specificity, PPV, NPV, and diagnostic accuracy were looked at. The data was examined using SPSS 24.0. Results: There were 27 (38.57%) female patients and 43 (61.43%) male patients. 39 patients (55.41%) were between the ages of 7 and 12 whereas 31 (44.29%) were between the ages of 0 and 6. By microscopic examination, 40 (57.14%) individuals tested positive for malaria, while 30 (42.86%) patients tested negative. By fast diagnostic test 29 (41.43%) people tested negative for malaria, while 41 (58.57%) people had malaria. Comparing the results of the two methods, it was found that 27 (38.57%) true negatives, 3 (4.29%) false positives, 2 (2.86%) false negatives, and 38 (54.29%) real positives. RDT has a 96.25% sensitivity, 90% specificity, 92.77% PPV, and 94.74% NPV. RDT’s diagnostic precision was 93.57%. Conclusion: The rapid diagnostic test is an useful diagnostic technique that can be used in place of a microscopic examination to diagnose malaria in children.
Abstract (English)
Background: In tropical nations, malaria is still a public health concern. In these nations, clinical evaluation, microscopy, the gold standard and more recently, rapid diagnostic tests (RDTs) are the mainstays of diagnosis. The purpose of this study is to evaluate the quick diagnostic test’s diagnostic accuracy for detecting malaria in children who have a clinical suspicion of having the disease. They used microscopy as the gold standard. Methods: This six-month cross-sectional and observational study was carried out at the SKMCH in Muzaffarpur, Bihar, from November 2022 to April 2023. In this study, 70 patients of both sexes with a clinical suspicion of malaria and ages up to 12 years were enrolled. Age, sexual orientation, and symptoms were noted in great detail. A quick diagnostic test was run, and the results were compared to microscopic analysis. Microscopy was regarded as the ultimate test. The Rapid Diagnostic Test’s sensitivity, specificity, PPV, NPV, and diagnostic accuracy were looked at. The data was examined using SPSS 24.0. Results: There were 27 (38.57%) female patients and 43 (61.43%) male patients. 39 patients (55.41%) were between the ages of 7 and 12 whereas 31 (44.29%) were between the ages of 0 and 6. By microscopic examination, 40 (57.14%) individuals tested positive for malaria, while 30 (42.86%) patients tested negative. By fast diagnostic test 29 (41.43%) people tested negative for malaria, while 41 (58.57%) people had malaria. Comparing the results of the two methods, it was found that 27 (38.57%) true negatives, 3 (4.29%) false positives, 2 (2.86%) false negatives, and 38 (54.29%) real positives. RDT has a 96.25% sensitivity, 90% specificity, 92.77% PPV, and 94.74% NPV. RDT’s diagnostic precision was 93.57%. Conclusion: The rapid diagnostic test is an useful diagnostic technique that can be used in place of a microscopic examination to diagnose malaria in children.
Files
IJPCR,Vol15,Issue7,Article195.pdf
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Additional details
Dates
- Accepted
-
2023-07-06
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue7,Article195.pdf
- Development Status
- Active
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