Neurological Manifestations of Post Covid Rhino Orbito Cerebral Mucormycosis – An Institutional Experience

Abstract
Introduction: An epidemic of Mucorales was reported following the second wave of COVID 19 in India, and
intracranial extension of the same was one of the most dreadful complications. The present study was done to
analyze the demographic data and provide an overview of the diverse clinico-radiological presentations of post
covid ROCM.
Materials and Methods: We systematically reviewed 30 patients diagnosed with post covid Rhino orbito
cerebral mucormycosis admitted at our hospital during MAY 2021 to JULY 2021.Data pertaining to
demographic variables, clinico-radiological features were analysed using percentage of total cases.
Results: A total of 30 patients with rhino orbito cerebral mucormycosis were enrolled in the study. The majority
of subjects were males. The most common age group affected was 41-50 years. History of preexisting diabetes
mellitus was recorded in 15 (67.35%) patients. Most common presenting symptom was facial pain (77%),
followed by drooping of eyelid and proptosis (73%) with 63% of the patients developing double vision.
Diminution of vision was seen in 40 % of the patients. Focal deficits were seen in 7 patients. Altered sensorium
was seen in 4 of them. Seizures were documented in two patients.
Conclusion: High index of suspicion with thorough knowledge of varied clinico-radiological presentations of
rhino orbito cerebral mucormycosis is necessary for prompt initiation of treatment and thereby aiding in
reduction of morbidity and mortality.