Assessment of Thyroid Dysfunction in Women with Normal Vs Preeclampsia Pregnancy: A Case Control Study
- 1. Associate Professor, Department of Obstetrics and Gynecology, MNR Medical College and Hospital, Sangareddy, Telangana, India
- 2. Associate Professor, Department of General Medicine, MNR Medical College and Hospital, Sangareddy, Telangana, India
Description
Introduction: Thyroid dysfunction has impending effect during pregnancy on both the mother and the fetus. Preeclampsia is a possible pregnancy-related complication in women with hypothyroidism. Th present study was aimed to assess the prevalence of hypothyroidism in the women with preeclampsia. Material and Methods: A total of 94 cases with preeclampsia between 18-35 years and age and gestational age matched control subjects belonged to >20 weeks were recruited. 5 ml of peripheral venous blood was collected to analyse free T3, free T4 and TSH levels. Results: The prevalence of hypothyroidism was 40.43% in women with preeclampsia. The TSH levels were comparatively high in women with severe preeclampsia than mild preeclampsia and levels of FT3, FT4 and TSH were comparatively high in preeclamptic women with >34 weeks of gestation. The number of antihypertensive drugs intake was significantly reduced after delivery in women with preeclampsia. Conclusion: Hypothyroidism was substantially correlated with the severity of preeclampsia. Women with conditions including obesity, diabetes, hypertension, and TSH should keep track of their levels regularly to prevent hypothyroidism, which can cause preeclampsia and have an effect on both the mother and the foetal outcome.
Abstract (English)
Introduction: Thyroid dysfunction has impending effect during pregnancy on both the mother and the fetus. Preeclampsia is a possible pregnancy-related complication in women with hypothyroidism. Th present study was aimed to assess the prevalence of hypothyroidism in the women with preeclampsia. Material and Methods: A total of 94 cases with preeclampsia between 18-35 years and age and gestational age matched control subjects belonged to >20 weeks were recruited. 5 ml of peripheral venous blood was collected to analyse free T3, free T4 and TSH levels. Results: The prevalence of hypothyroidism was 40.43% in women with preeclampsia. The TSH levels were comparatively high in women with severe preeclampsia than mild preeclampsia and levels of FT3, FT4 and TSH were comparatively high in preeclamptic women with >34 weeks of gestation. The number of antihypertensive drugs intake was significantly reduced after delivery in women with preeclampsia. Conclusion: Hypothyroidism was substantially correlated with the severity of preeclampsia. Women with conditions including obesity, diabetes, hypertension, and TSH should keep track of their levels regularly to prevent hypothyroidism, which can cause preeclampsia and have an effect on both the mother and the foetal outcome.
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IJPCR,Vol15,Issue7,Article34.pdf
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Additional details
Dates
- Accepted
-
2023-05-30
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue7,Article34.pdf
- Development Status
- Active
References
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