An Observational Study Assessing the Correlation between ClinicoRadiological Profiles with Histopathological Patterns of Lung Cancer

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Abstract (English)

Abstract
Aim: The aim of the present study was to find out the correlation between clinico-radiological profiles with
histopathological patterns of lung cancer.
Methods: This was a cross-sectional observational study conducted at over a duration of 1 year patients with
histopathologically confirmed lung cancer. A total of 200 histopathologically confirmed diagnosed patients with
lung cancer were included in the study.
Results: There were 36% and 35% of patients who belonged to age between 51-60 year and 60-70 year
respectively. Out of 200 patients, 170 patients were smokers, 90 patients had a prior history of COPD, and
lymphadenopathy was present in 20 patients. The ECOG performance status 37% of patients remained on scale
2, followed by 35% on scale 3. Among the clinical symptoms, cough was present in (85%), breathlessness
(60%), chest pain (56%) followed by hemoptysis, sputum production, voice change, and superior vena cava
obstruction. Radiological examination showed mass lesion as the most common finding (80%) followed by
collapse (9%) and pleural effusion (5%). Correlation of histopathological types with radiological findings
showed that mass lesion was the major finding in both adenocarcinoma and squamous cell carcinoma. Pleural
effusion was present in about more than half of the patients with adenocarcinoma. Lymphadenopathy was only
present in adenocarcinoma.
Conclusion: This study showed that smoking is a principal risk factor in causation of lung carcinoma. It was
seen to present more frequently in elderly age groups. Patients commonly present with chief complaints of
smoking and breathlessness. Further investigations should be carried out in such circumstances to confirm the
diagnosis