A Retrospective Record-Based Clinico-Epidemiological Assessment of Thalassemia Patients: An Observational Study
Authors/Creators
- 1. Junior Resident, Upgraded Department of Pediatrics, Patna Medical College and Hospital, Patna, Bihar, India
- 2. Professor, Upgraded Department of Pediatrics, Patna Medical College and Hospital, Patna, Bihar, India
Description
Abstract
Aim: Thea aim of the present study was to assess the pattern, clinical presentations, complications, and
management practices among thalassemia cases
Material & Methods: This was a retrospective record-based cross-sectional study was conducted in the
Upgraded Department of Pediatrics. The secondary data of all confirmed cases of thalassemia were examined by
the investigators. 100 patients were included in the study.
Results: The mean age of cases was 6.4 years. The age at diagnosis ranged from 0.1 to 11 years. The majority
of cases were between 1.1-5 was 36 (36%) and 64 were male. 70% were above poverty line and 85% belonged
to urban area. Fever was the most common presenting symptom 17 (17%). Pallor 98 (98%) followed by
hepatomegaly 94 (94%) were the most common signs among cases. Bone deformities were reported in 20 (20%)
cases, all of which were beta thalassemia major cases.
Conclusion: Hemoglobinopathies are the commonest hereditary disorders in India and pose a major health
problem. The data on the prevalence of β-thalassemia’s and other hemoglobinopathies in different caste/ethnic
groups of India is scarce
Abstract (English)
Abstract
Aim: Thea aim of the present study was to assess the pattern, clinical presentations, complications, and
management practices among thalassemia cases
Material & Methods: This was a retrospective record-based cross-sectional study was conducted in the
Upgraded Department of Pediatrics. The secondary data of all confirmed cases of thalassemia were examined by
the investigators. 100 patients were included in the study.
Results: The mean age of cases was 6.4 years. The age at diagnosis ranged from 0.1 to 11 years. The majority
of cases were between 1.1-5 was 36 (36%) and 64 were male. 70% were above poverty line and 85% belonged
to urban area. Fever was the most common presenting symptom 17 (17%). Pallor 98 (98%) followed by
hepatomegaly 94 (94%) were the most common signs among cases. Bone deformities were reported in 20 (20%)
cases, all of which were beta thalassemia major cases.
Conclusion: Hemoglobinopathies are the commonest hereditary disorders in India and pose a major health
problem. The data on the prevalence of β-thalassemia’s and other hemoglobinopathies in different caste/ethnic
groups of India is scarce
Files
IJCPR,Vol15,Issue10,Article19.pdf
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Additional details
Dates
- Accepted
-
2023-04-22