An Observational Study to Determine the Importance of OesophagoGastroscopy in the Diagnostics of Laryngopharyngeal Reflux (LPR)
Authors/Creators
- 1. 1 Senior Consultant and HOD, Department of Gastroenterology and Hepatology, DIRECTOR Advanced GI Endoscopy, Mediversal, Hospital, Patna, Bihar, India
- 2. Senior Resident, Department of ENT, NMCH, Patna, Bihar, India
- 3. Resident, Department of Gastroenterology, Mediversal, Hospital, Patna, Bihar, India
Description
Abstract
Aim: The aim of the present study was to determine the importance of oesophago-gastroscopy in the diagnostics
of laryngopharyngeal reflux (LPR) induced pathology.
Methods: The present study was conducted in the Department of Gastroenterology, A total of 50 patients (30
women, 20 men) with laryngopharyngeal problems in whom GERD was suspected were included in the study.
They were 17 −/78 years old, with a mean of 45 years and a standard deviation of 14.6 years.
Results: The VHI results showed that patients with vocal fold polyps assessed their voice problems as being
worse in comparison to the voice problems of the LPR patients, but the significant difference appeared only in the
physical subtest of VHI. The subjective VHI test performed in the LPR patients after the treatment showed a
significant improvement in the overall results and in the results of all the subtests in comparison to the results of
the test performed before the treatment. The acoustic analysis of the voice samples detected almost no change in
F0 and JIT and a statistically significant improvement in SH and NHR. On the basis of videoendolaryngoscopy,
the lesions of the laryngeal mucosa were evaluated using the BRFS before and after the treatment with
esomeprasol. In all the LPR patients the BRFS was more than 7 before the treatment, indicating LPR. After the
treatment, the BRFS significantly decreased.
Conclusion: LPR can cause serious voice disorders, globus pharyngeus sensation, or frequent coughing. The
voice problems can be compared to the problems of patients with vocal fold polyps. Oesophago-gastroscopy
supplemented with a biopsy of the oesophageal mucosa can be a suitable method to prove the occurrence of GER.
Videoendolaryngoscopy and the BRFS are superior in the diagnostics of LPR and correlate very well with the
histological findings of the oesophageal mucosa specimens. The combination of all three procedures is supposed
to be a very successful method in the diagnostics of GERD and especially LPR. Esomeprasol proved to be very
effective in the treatment of LPR.
Abstract (English)
Abstract
Aim: The aim of the present study was to determine the importance of oesophago-gastroscopy in the diagnostics
of laryngopharyngeal reflux (LPR) induced pathology.
Methods: The present study was conducted in the Department of Gastroenterology, A total of 50 patients (30
women, 20 men) with laryngopharyngeal problems in whom GERD was suspected were included in the study.
They were 17 −/78 years old, with a mean of 45 years and a standard deviation of 14.6 years.
Results: The VHI results showed that patients with vocal fold polyps assessed their voice problems as being
worse in comparison to the voice problems of the LPR patients, but the significant difference appeared only in the
physical subtest of VHI. The subjective VHI test performed in the LPR patients after the treatment showed a
significant improvement in the overall results and in the results of all the subtests in comparison to the results of
the test performed before the treatment. The acoustic analysis of the voice samples detected almost no change in
F0 and JIT and a statistically significant improvement in SH and NHR. On the basis of videoendolaryngoscopy,
the lesions of the laryngeal mucosa were evaluated using the BRFS before and after the treatment with
esomeprasol. In all the LPR patients the BRFS was more than 7 before the treatment, indicating LPR. After the
treatment, the BRFS significantly decreased.
Conclusion: LPR can cause serious voice disorders, globus pharyngeus sensation, or frequent coughing. The
voice problems can be compared to the problems of patients with vocal fold polyps. Oesophago-gastroscopy
supplemented with a biopsy of the oesophageal mucosa can be a suitable method to prove the occurrence of GER.
Videoendolaryngoscopy and the BRFS are superior in the diagnostics of LPR and correlate very well with the
histological findings of the oesophageal mucosa specimens. The combination of all three procedures is supposed
to be a very successful method in the diagnostics of GERD and especially LPR. Esomeprasol proved to be very
effective in the treatment of LPR.
Files
IJCPR,Vol15,Issue11,Article120.pdf
Files
(332.6 kB)
| Name | Size | Download all |
|---|---|---|
|
md5:36ca8804aeea950cd972e830af78a553
|
332.6 kB | Preview Download |
Additional details
Dates
- Accepted
-
2023-11-29