An Analytical Cross-Sectional Study Assessing Correlation of MPV with Fasting Blood Glucose, Glycosylated Hemoglobin (Hba1c) and Duration of Diabetes in the Diabetic Patients
Authors/Creators
- 1. Tutor, Department of Pathology, Government Medical College and Hospital, Bettiah, West Champaran, Bihar, India
- 2. Associate Professor & HOD, Department of Pathology, Government Medical College and Hospital, Bettiah, West Champaran, Bihar, India
Description
Abstract
Aim: The aim of the present study was to determine the correlation of MPV with fasting blood glucose,
glycosylated hemoglobin (HbA1c) and duration of diabetes in the diabetic patients.
Material & Methods: This was a cross-sectional study carried out in Department of Pathology, including 200
patients who were already diagnosed to have Type 2 DM and 200 nondiabetic subjects without known coronary
artery disease in between the duration of 12 months
Results: There were more male as compared to females in both groups. MPV was significantly raised in the
diabetic population in comparison to controls. Similarly, we also observed significantly higher MPV among
diabetics with vascular complications in comparison to those without vascular complications. Among diabetics
with microvascular complications, MPV showed a significant association with Diabetic Nephropathy and Diabetic
retinopathy. Similarly, among those with macrovascular complications, MPV showed a significant association
with Peripheral Artery Disease. MPV showed significant positive correlation with HbA1C, fasting blood sugar,
and duration of diabetes in our study. All three correlations are reflected by their positive "r" values.
Conclusion: Results showed significantly higher MPV in diabetic patients than in the nondiabetic subjects. This
indicates that elevated MPV could be either the cause for or due to the effect of the vascular complications. Hence,
platelets may play a role and MPV can be used as a simple parameter to assess the vascular events in diabetes
Abstract (English)
Abstract
Aim: The aim of the present study was to determine the correlation of MPV with fasting blood glucose,
glycosylated hemoglobin (HbA1c) and duration of diabetes in the diabetic patients.
Material & Methods: This was a cross-sectional study carried out in Department of Pathology, including 200
patients who were already diagnosed to have Type 2 DM and 200 nondiabetic subjects without known coronary
artery disease in between the duration of 12 months
Results: There were more male as compared to females in both groups. MPV was significantly raised in the
diabetic population in comparison to controls. Similarly, we also observed significantly higher MPV among
diabetics with vascular complications in comparison to those without vascular complications. Among diabetics
with microvascular complications, MPV showed a significant association with Diabetic Nephropathy and Diabetic
retinopathy. Similarly, among those with macrovascular complications, MPV showed a significant association
with Peripheral Artery Disease. MPV showed significant positive correlation with HbA1C, fasting blood sugar,
and duration of diabetes in our study. All three correlations are reflected by their positive "r" values.
Conclusion: Results showed significantly higher MPV in diabetic patients than in the nondiabetic subjects. This
indicates that elevated MPV could be either the cause for or due to the effect of the vascular complications. Hence,
platelets may play a role and MPV can be used as a simple parameter to assess the vascular events in diabetes
Files
IJCPR,Vol15,Issue11,Article115.pdf
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Additional details
Dates
- Accepted
-
2023-10-24