Formulation And Evaluation Of Herbal Gel

In the present study, three medicinal plants Cynodon dactylon (L.) Pers, Cassia tora Linn. and Cassia alata Linn having significant anti-inflammatory potential were selected to be formulated as polyherbal gels. The gels were prepared using the dried methanolic extract of Cassia tora Linn, Cassia alata Linn and Cynodon dactylon (L.) Pers. Polyherbal gel formulations were evaluated for its pH, appearance and homogeneity, viscosity, spreadability and skin irritation studies. Assessment of Anti-inflammatory activity was done by carrageenan induced rat paw edema and formalin- induced rat paw edema. Individual and polyherbal gel of Cassia alata Linn,Cassia tora Linn. and Cynodon dactylon(L.) Pers were found to possess anti-inflammatory effect in acute and chronic models. Polyherbal gel also showed synergistic effect as compared to individual gels which can be useful for the treatment of local inflammation. Herbal gel is a solid, jelly-like substance that can have properties ranging from soft and weak to hard and tough preparation. It is used topically for a variety of purposes, such as protectants, antiseptics, and antimicrobials. The herbal gel was made by combining Azadirachta indica, Curcuma longa, Berberis aristata, and Rubia cordifolia. Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli were used as test subjects for the antibacterial activity. It was shown that the herbal gel had the strongest effect on Staphylococcus aureus (Hand bacteria). To fully understand the mechanism of action and to create a formulation that can be useful in the health sector, more research is required.