Published September 3, 2014
| Version v1
Dataset
Open
Kinase Inhibitors and Scaffolds
Authors/Creators
- 1. Department of Life Science Informatics, B-IT, LIMES Program Unit Chemical Biology and Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Dahlmannstr. 2, D-53113 Bonn, Germany.
Description
On the basis of the assessment of compound and scaffold coverage of human kinome, sets of kinase inhibitors and scaffolds with high-confidence activity data assembled from ChEMBL release 18 are provided. In addition, sets of scaffolds involving in different types of structural relationships, having varying degrees of promiscuity and representing highly potent inhibitors are made available. A documentation file (i.e., README.txt) is given.