Published August 30, 2023 | Version https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue8,Article284.pdf
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Comparative Study of Intrathecal Fentanyl and Buprenorphine as an Adjuvant to 0.5% Hyperbaric Bupivacaine in Spinal Anaesthesia for Lower Abdominal and Lower Limb Surgery in Adults

  • 1. Senior Resident, Department of Anaesthesia, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar
  • 2. Assistant Professor and Head of Department, Department of Anaesthesia, Sri Krishna Medical College & Hospital, Muzaffarpur, Bihar

Description

Background: Neural axial blockade is the recommended type of anesthesia for lower limb procedures. Because of its quick onset, superior blockade, lower failure rates, and cost-effectiveness, spinal block is still the preferred treatment. The current study compares the effectiveness of intrathecal bupivacaine combined with buprenorphine and fentanyl in orthopaedic procedures involving the lower limbs. Method: Five patients were excluded because they did not meet the inclusion criteria out of 89 scheduled patients for lower abdomen and lower limb surgery. By using a computer-generated random number sequence, the remaining 84 patients were randomly split into two groups. The dosage for Group B was 50 μg of buprenorphine and 3 cc (15 mg) of strong Bupivacaine. Group F received 3cc (15mg) of Bupivacaine (heavy) and 25μg of fentanyl. Results: When combined with bupivacaine, buprenorphine, and fentanyl, spinal anesthesia offers high-quality intraoperative and postoperative analgesia. Sensory and motor blocks are greatly prolonged by buprenorphine and bupropion. Buprenorphine group has longer analgesia and sedation durations than Fentanyl group. Conclusion: Both groups’ hemodynamic stability was equivalent and statistically insignificant.

 

 

Abstract (English)

Background: Neural axial blockade is the recommended type of anesthesia for lower limb procedures. Because of its quick onset, superior blockade, lower failure rates, and cost-effectiveness, spinal block is still the preferred treatment. The current study compares the effectiveness of intrathecal bupivacaine combined with buprenorphine and fentanyl in orthopaedic procedures involving the lower limbs. Method: Five patients were excluded because they did not meet the inclusion criteria out of 89 scheduled patients for lower abdomen and lower limb surgery. By using a computer-generated random number sequence, the remaining 84 patients were randomly split into two groups. The dosage for Group B was 50 μg of buprenorphine and 3 cc (15 mg) of strong Bupivacaine. Group F received 3cc (15mg) of Bupivacaine (heavy) and 25μg of fentanyl. Results: When combined with bupivacaine, buprenorphine, and fentanyl, spinal anesthesia offers high-quality intraoperative and postoperative analgesia. Sensory and motor blocks are greatly prolonged by buprenorphine and bupropion. Buprenorphine group has longer analgesia and sedation durations than Fentanyl group. Conclusion: Both groups’ hemodynamic stability was equivalent and statistically insignificant.

 

 

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Dates

Accepted
2023-08-18

References

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