Canine duodenum scRNA-seq atlas

This release adds the processed data to ensure the data are accessible. The relevant manuscript is, "Single cell transcriptomic analysis of the canine duodenum in chronic inflammatory enteropathy and health."

File descriptions

• AllCells_duod_annotated.rds - Seurat object (version 4.3.0) of the full dataset used in generation of Figure 2. with annotations stored in the `celltype.l1` and `celltype.l2` metadata slots.
• Myeloid_duod_annotated.rds - Seurat object (version 4.3.0) of the myeloid cell subset used in generation of Figure 3. Annotations tored in the `celltype.l1` and `celltype.l2` metadata slots.
• Tcell_duod_annotated.rds - Seurat object (version 4.3.0) of the T cell subset used in generation of Figure 4d. Annotations tored in the `celltype.l1` and `celltype.l2` metadata slots.
• Epithelial_duod_annotated.rds - Seurat object (version 4.3.0) of the epithelial cell subset used in generation of Figure 5. Annotations tored in the `celltype.l1` and `celltype.l2` metadata slots.

Additional resources

• NCBI GEO: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE254005
• Interactive cell browser: https://canine-duodenum-cie.cells.ucsc.edu
• GitHub page: https://github.com/dyammons/canine_duodenal_atlas

Key words: canine, duodenum, scRNA-seq, transcriptomics, chronic enteropathy, canine (dog)