FACTORS AFFECTING THE FORMATION OF INTESTINAL MICROFLORA AND THE DEVELOPMENT OF ATOPIC DERMATITIS IN INFANTS BORN OF MOTHERS PROPRIETARY TO ALLERGIC REACTIONS

Abstract

The human microbiota is an ecological system that has developed as a result of the evolution of various microorganisms that inhabit the open spaces of the body and provide the biochemical, metabolic and immunological balance necessary to protect health [1]. The largest population of microbes is found in the gastrointestinal tract, especially the large intestine. Thus, about 1014 bacterial cells live in the human large intestine, which is ten times more than the total number of cells in the body [2]. The microbiota of each person has a unique composition and develops throughout life [4]. Intestinal microflora is of great importance for human health, ensuring the continuity of colonization of the mucous membranes of the digestive system, regulating important metabolic and physiological functions, stimulating the development of the immune system and maintaining the homeostasis of the body. From this point of view, the process of formation of the intestinal microbiota is of great interest. In this article we present the results of our research in the direction of identifying factors influencing the formation of intestinal microflora in newborns and the development of atopic dermatitis in these babies born from mothers prone to allergic reactions.