Published May 29, 2024 | Version 1.0
Dataset Open

Trypanosoma Epitope Dataset: Valid Epitopes and Randomly Generated Peptides with Biochemical Metrics and AI-Generated Scores

Authors/Creators

  • 1. ROR icon Instituto Federal de Educação, Ciência e Tecnologia de Santa Catarina
  • 2. ROR icon Universidade Federal de Santa Catarina
  • 3. Universidad Tecnológica del Uruguay
  • 4. ROR icon Universidade Federal de Ciências da Saúde de Porto Alegre

Description

This dataset contains information about valid linear B-Cell epitopes from the Trypanosoma genus, as well as randomly generated peptides. It includes biochemical metrics generated by the EpiBuilder-1.0 tool and scores generated by the BepiPred-3.0 software. The data was originally collected from the IEDB and UniProtKB platforms and has been processed and enhanced with these informations for researchers interested in understanding the molecular interactions between Trypanosoma protozoans and the immune system.

Files

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Additional details

Additional titles

Translated title (Portuguese)
Conjunto de dados de Epítopos de Trypanosoma: Epítopos Válidos e Peptídeos Gerados Aleatoriamente com Métricas Bioquímicas e Scores Gerados por IA
Translated title (Spanish)
Conjunto de datos de Epítopos de Trypanosoma: Epítopos Válidos y Péptidos Generados Aleatoriamente con Métricas Bioquímicas y Scores Generados por IA

References

  • Moreira RS, Filho VB, Calomeno NA, Wagner G, Miletti LC. EpiBuilder: A Tool for Assembling, Searching, and Classifying B-Cell Epitopes. Bioinform Biol Insights. 2022 May 11;16:11779322221095221. doi: 10.1177/11779322221095221. PMID: 35571557; PMCID: PMC9102138.
  • Clifford JN, Høie MH, Deleuran S, Peters B, Nielsen M, Marcatili P. BepiPred-3.0: Improved B-cell epitope prediction using protein language models. Protein Sci. 2022 Dec;31(12):e4497. doi: 10.1002/pro.4497. PMID: 36366745; PMCID: PMC9679979.
  • Vita R, Mahajan S, Overton JA, Dhanda SK, Martini S, Cantrell JR, Wheeler DK, Sette A, Peters B. The Immune Epitope Database (IEDB): 2018 update. Nucleic Acids Res. 2018 Oct 24. doi: 10.1093/nar/gky1006. PMID: 30357391; PMCID: PMC6324067
  • The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2023, Nucleic Acids Research, Volume 51, Issue D1, 6 January 2023, Pages D523–D531, https://doi.org/10.1093/nar/gkac1052