Mortality Profile, Risk Factors, and Aetiology Associated with Neonatal Hyperbilirubinemia
Authors/Creators
- 1. Senior Resident, Department of Paediatrics, BMIMS, Pawapuri, Nalanda, Bihar, India
- 2. Assistant Professor, Department of Pediatrics, BMIMS, Pawapuri, Nalanda, Bihar, India
Description
Background: The most usual and chronic early disease that affects the newborn is Hyperbilirubinemia otherwise called jaundice. This disease often requires immediate treatment and detection and may also require readmittance to the hospital for complete diagnosis. The occurrence of hyperbilirubinemia in neonates is estimated to be 65% – 85% approximately. This study deals with the analysis of etiology, risk factors and morbidity of hyperbilirubinemia in neonates at a tertiary care hospital. Materials and Methods: It was a prospective study which was conducted at a tertiary care centre in BMIMS Pawapuri (Nalanda) Bihar with newborn babies and also babies aged from 0 to 28 days were included in this study. Results: A total of 50 neonatal babies were included in this study of which 30 were male and 20 were female babies. Of the 50 neonatal babies selected, 15 were less than 37 weeks development and the remaining 35 were more than 37 weeks development. Conclusion: The primary cause for neonatal hyperbilirubinemia was ABO incompatibility and spontaneous jaundice continued by Rh factor and blood poisoning by bacteria. Elevated bilirubin levels are the initial symptoms of hyperbilirubinemia. Phototherapy is an excellent tool for diagnosing this disease in neonates and helps in reducing the levels of bilirubin in newborn babies.
Abstract (English)
Background: The most usual and chronic early disease that affects the newborn is Hyperbilirubinemia otherwise called jaundice. This disease often requires immediate treatment and detection and may also require readmittance to the hospital for complete diagnosis. The occurrence of hyperbilirubinemia in neonates is estimated to be 65% – 85% approximately. This study deals with the analysis of etiology, risk factors and morbidity of hyperbilirubinemia in neonates at a tertiary care hospital. Materials and Methods: It was a prospective study which was conducted at a tertiary care centre in BMIMS Pawapuri (Nalanda) Bihar with newborn babies and also babies aged from 0 to 28 days were included in this study. Results: A total of 50 neonatal babies were included in this study of which 30 were male and 20 were female babies. Of the 50 neonatal babies selected, 15 were less than 37 weeks development and the remaining 35 were more than 37 weeks development. Conclusion: The primary cause for neonatal hyperbilirubinemia was ABO incompatibility and spontaneous jaundice continued by Rh factor and blood poisoning by bacteria. Elevated bilirubin levels are the initial symptoms of hyperbilirubinemia. Phototherapy is an excellent tool for diagnosing this disease in neonates and helps in reducing the levels of bilirubin in newborn babies.
Files
IJPCR,Vol15,Issue10,Article143.pdf
Files
(290.7 kB)
| Name | Size | Download all |
|---|---|---|
|
md5:21de5bf989198418c0d168d69ae88b75
|
290.7 kB | Preview Download |
Additional details
Dates
- Accepted
-
2023-10-05
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue10,Article143.pdf
- Development Status
- Active
References
- 1. Avery G B, Maisels MJ Jaundice, Pathophysiology and management of newborns. 5th ed. Philadelphia: Lippincott JB Company; 1999. 2. Taeush, Ballard, Gleason. Avery's Diseases of the Newborn. 8th ed. Philadelphia Elsevier; 2005. 3. Anand VR, Magotra ML. Neonatal Jaundice: Its Incidence and Aetiology. Indian Pediatr. Feb 1978;15(2):155-60. 4. Sharma J, Sharma R, Bahl L. Etiology of neonatal Jaundice at Shimla. Indian Pediatr. Oct 1994; 31:1275-78. 5. Behrmann RE, Hsia DYY. Summary of a symposium on phototherapy for hyperbilirubinemia. J Pediatr. 1969;75(4):718-26. 6. Johnson L, Bhutani VK. Guidelines for the management of the jaundiced term and near term infant. Clin Perinatol. Sept 1998; 25(3): 555-74. 7. Gathwala G, Kumar P. Neonatal Jaundice: Indian Pediatr. May 1997;34:429-32. 8. Lochmann KK, Sodhi M, Singh G. Incidence of neonatal jaundice. Abstracts Pedicon. 2004; 158-59. 9. Ramesh Agarwal, A.K. Deorari: Unconjugated hyperbilirubinemia in newborns: Current perspective; Indian Pediatrics. 2002; 39:30-32. 10. Misra P.K. and Govil Y.C. Neonatal hyperbilirubinemia; IAP Journal of Practical Pediatrics, 1994; 2 (4):361-366. 10. Phyllis A. Denney, William D. Rhine, David K. Stevenson: Neonatal jaundice - What now? Clinical Pediatrics, 1995; 103-105. 11. Narang A, Gathimala G, and Praveen Kumar: Neonatal jaundice: an analysis of 551 cases; Indian Paediatrics, 2001; 68:977-980. 12. Singhal P.K., Meherban Singh, V. K. Paul, A.K. Deorari, and M.G. Ghorpade: Spectrum of neonatal hyperbilirubinemia. An analysis of 454 cases, Indian Paediatrics, 1992; 29: 319-32 5. 13. Merchant R. H., Merchant S.M. and Barbar S.T.: A study of 75 cases of neonatal jaundice; Indian Paediatrics, 1975; XII (9) 889-893. 14. Verma Manorama, Jugesh Chatwal and Daljit Singh: Neonatal hyperbilirubinemia; Indian Journal of Paediatrics. 1988; 55: 899-904.