A Study of Serum Magnesium Levels in AcuteMyocardial Infarction
Authors/Creators
- 1. Assistant Professor, Department of General Medicine, SUT Academy of Medical Sciences, Vencode, Trivandrum, Kerala
- 2. Associate Professor, Department of Otorhinolaryngology, Shri Sathya Sai Medical College and Research Institute, Chennai, Tamil Nadu
- 3. Assistant Professor, Department of Otorhinolaryngology, PSP Medical College Hospital and Research Institute, Tamil Nadu
Description
Background: Magnesium has been implicated in the pathogenesis of acute myocardial infarction and its complication like arrhythmia. Magnesium improves vascular tone, peripheral vascular resistance, after load and cardiac output, reduces cardiac arrhythmias and improves lipid metabolism. Magnesium also reduces vulnerability to oxygen derived free radicals, improves endothelial function and inhibits platelet function including platelet aggregation and adhesion. Objective: To know the relationship between the serum magnesium levels and arrhythmias in patients with acute myocardial infarction. Method: By using simple random method, 50 cases of acute myocardial infarction, admitted in Basaveshwar Teaching & General Hospital, attached to M.R.Medical College, Gulbarga over a period of 2 years i.e., between October 2006 to March 2008. Results: There is a significant difference in the magnesium levels in patients with arrhythmias and without arrhythmias. Conclusion: In acute myocardial infarction, patients with low magnesium levels are more prone to get arrhythmias. So magnesium treatment can be considered in patients of acute myocardial infarction with low magnesium levels.
Abstract (English)
Background: Magnesium has been implicated in the pathogenesis of acute myocardial infarction and its complication like arrhythmia. Magnesium improves vascular tone, peripheral vascular resistance, after load and cardiac output, reduces cardiac arrhythmias and improves lipid metabolism. Magnesium also reduces vulnerability to oxygen derived free radicals, improves endothelial function and inhibits platelet function including platelet aggregation and adhesion. Objective: To know the relationship between the serum magnesium levels and arrhythmias in patients with acute myocardial infarction. Method: By using simple random method, 50 cases of acute myocardial infarction, admitted in Basaveshwar Teaching & General Hospital, attached to M.R.Medical College, Gulbarga over a period of 2 years i.e., between October 2006 to March 2008. Results: There is a significant difference in the magnesium levels in patients with arrhythmias and without arrhythmias. Conclusion: In acute myocardial infarction, patients with low magnesium levels are more prone to get arrhythmias. So magnesium treatment can be considered in patients of acute myocardial infarction with low magnesium levels.
Files
IJPCR,Vol15,Issue10,Article38.pdf
Files
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Additional details
Dates
- Accepted
-
2023-09-30
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue10,Article38.pdf
- Development Status
- Active
References
- 1. Burch GE, Gibs TD. Importance of magnesium deficiency in cardiovascular disease. American Heart Journal. 1977; 94: 649. 2. Rubenowitz E, Molin I, Axelsson G, Rylander R. Magnesium in drinking water in relation to morbidity and mortality from acute myocardial infarction. Epidemiology. 2000 Jul 1:416-21. 3. Crawford T et al. Prevalence and pathological changes of ischemic heart disease in hard water and in a soft water area. Lancet. 1967; 1: 229. 4. Ceremuzynski L, Jurgiel R et al. Threatening arrhythmias in acute myocardial infarction are prevented by intravenous magnesium sulphate. Am Heart J. 1989; 118: 1333-1334. 5. Shechter M, Mark N et al. Beneficial effects of magnesium sulphate in acute myocardial infarction. Am J Cardiol. 1990; 66: 271-274. 6. Smith LF, Heagerty AM. Intravenous infusion of magnesium sulphate after acute myocardial infarction: Effects on arrhythmias and mortality. Int J Cardiol. 1986; 12: 175-180. 7. Felstedt M, Boesgarurd et al. Magnesium substitution in acute ischaemic heart syndrome. Eur Heart J. 1991; 12: 1215-1218. 8. Singh RB, Sircar AR et al. Magnesium and potassium administration in acute myocardial infarction. Magnesium Trace Elem. 1990; 9: 198-204. 9. Morton BC, Nair RC et al. Magnesium therapy in acute myocardial infarction: A double blind study. Magnesium. 1984; 3: 346-352. 10. Dyckner T. Serum magnesium in acute myocardial infarction: Relation to Arrhythmias. Acta med scan 1980; 207:59-66.