Correlation of Clinical and Biochemical Parameters in Liver Abscess Patients at Tertiary Centre of North Bihar
Authors/Creators
- 1. Senior Resident, Department of Medicine, Sri Krishna Medical College and Hospital (SKMCH), Muzaffarpur, Bihar
- 2. Professor, Department of Medicine, Sri Krishna Medical College and Hospital (SKMCH), Muzaffarpur, Bihar
Description
Background: 48 percent of all visceral abscesses are located in the liver. Due to inadequate nutrition, overcrowding, and poor sanitation, it is frequent in India, where it has the second highest prevalence. An estimated 40–50 million individuals worldwide contract amoebic abscesses each year. In order to provide a timely diagnosis and effective treatment, the purpose of this study is to monitor the clinical and biochemical characteristics of patients suffering from liver abscesses at the tertiary center set up in North Bihar. Methods: The study examined 50 liver abscess patients and was carried out over a 12-month period. A physical examination and history were taken. A full hemogram, a liver function test, a coagulation profile (PT/INR), and an abdominal USG were performed on each patient. HIV and Entamoeba histolytica serology were performed. Results: The patients were 41.8 years old on average, with a male preponderance. The majority of liver abscesses were amoebic (86%) as opposed to pyogenic (14%). Diabetes mellitus (20%) and alcoholism (52%) are the two main risk factors for hepatic abscess. In 80% of instances, hepatomegaly was detected. Low albumin, elevated PT INR, and elevated ALP all suggest a liver abscess. Right lobe abscesses accounted for 76% of all abscesses, and 66% of them were solitary. Pleural effusion (6%), and ascites (12%) were the observed complications. Conclusion: Patients who come with a protracted fever and right upper quadrant abdominal pain may have a liver abscess, especially if they have diabetes mellitus or are alcoholism. The use of ultrasonography is a simple and affordable method of diagnosing liver abscess. A strong foundation for preventing complications, morbidity, and death is early and aggressive treatment.
Abstract (English)
Background: 48 percent of all visceral abscesses are located in the liver. Due to inadequate nutrition, overcrowding, and poor sanitation, it is frequent in India, where it has the second highest prevalence. An estimated 40–50 million individuals worldwide contract amoebic abscesses each year. In order to provide a timely diagnosis and effective treatment, the purpose of this study is to monitor the clinical and biochemical characteristics of patients suffering from liver abscesses at the tertiary center set up in North Bihar. Methods: The study examined 50 liver abscess patients and was carried out over a 12-month period. A physical examination and history were taken. A full hemogram, a liver function test, a coagulation profile (PT/INR), and an abdominal USG were performed on each patient. HIV and Entamoeba histolytica serology were performed. Results: The patients were 41.8 years old on average, with a male preponderance. The majority of liver abscesses were amoebic (86%) as opposed to pyogenic (14%). Diabetes mellitus (20%) and alcoholism (52%) are the two main risk factors for hepatic abscess. In 80% of instances, hepatomegaly was detected. Low albumin, elevated PT INR, and elevated ALP all suggest a liver abscess. Right lobe abscesses accounted for 76% of all abscesses, and 66% of them were solitary. Pleural effusion (6%), and ascites (12%) were the observed complications. Conclusion: Patients who come with a protracted fever and right upper quadrant abdominal pain may have a liver abscess, especially if they have diabetes mellitus or are alcoholism. The use of ultrasonography is a simple and affordable method of diagnosing liver abscess. A strong foundation for preventing complications, morbidity, and death is early and aggressive treatment.
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IJPCR,Vol15,Issue12,Article145.pdf
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Additional details
Dates
- Accepted
-
2023-11-30
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue12,Article145.pdf
- Development Status
- Active
References
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