SYNTHESIS, CHARACTERIZATION AND ANTI-MICROBIAL ACTIVITY OF 2,5DIMETHYL PYRROLE

Aim: Synthesis of some pyrrole derivatives from condensation of acetonylacetone with ammonium carbonate Yields  the 2,5 Dimethyl pyrrole and evaluate the potential antimicrobial activity.

Method: Reflexation of acetonylacetone with ammonium carbonate with the support of oil bath at 100 °Caround 60 minutes on cooling reaction mixture.The yellow layer is separated and extracted with chloroform on evaporation of chloroform we yield product .

Result:This molecules exhibits moderate to good antimicrobial activity .Which are comparable to standards used in this study.

Conclusion:The result of 2,5 Dimethylpyrrole indicates that a number of this molecules exhibits moderate to good antibacterial ,antifungal activities and this class of compounds as potential leads towards antimicrobial agents .

Keywords: Dimethylpyrrole,Reflux,Antimicrobial.