Thyroidal Hormonal Variations - A Neglected Entity in Type II Diabetes Mellitus
Authors/Creators
- 1. Associate Professor, Department of Biochemistry Government Medical College Ananthapuramu, Andhra Pradesh
- 2. Assistant Professor, Department of Anatomy, Kurnool Medical College, Kurnool
- 3. Associate Professor, Department of Biochemistry, Government Medical College Nandyala, Andhra Pradesh
- 4. Associate Professor, Department of Biochemistry, Government Medical College, Kadapa, Andhra Pradesh
- 5. Professor, Department of Biochemistry Government Medical College Ananthapuramu, Andhra Pradesh
- 6. Associate Professor, Dept. of Community Medicine Government Medical College, Ananthapuramu, Andhra Pradesh
Description
Introduction: The co-existence of thyroid dysfunction in type 2 diabetes mellitus patients will worsen the macrovascular and microvascular complications, morbidity, mortality, and quality of life. Over the years it has been evident that there exists regards a strong relationship between thyroid and diabetes. The incidence of thyroid diseases differs in different diabetic population. Thyroid through its hormones exert a great influence on various organs in the body. Similarly insulin also plays a major role in various cellular metabolic activities. Hence, a deficiency or excess of the thyroid hormones are thought to alter the functional integrity of insulin. Aim and Objective: The objective of this study was to determine the prevalence of thyroid dysfunction among patients with Type 2 diabetes. Methods: This Hospital based prospective cross sectional study was conducted from May 2022- May 2023. A total of 100 patients with type-2 diabetes who regularly attend the outpatient Endocrinology Department, GGH Ananthapuramu. A detailed history and examination was done after getting informed consent. Blood samples were collected and sent to the laboratory for the evaluation of thyroid profile. Results: Thyroid dysfunction was found in 36%of the patients with Type 2 DM. Among 100 patients the prevalence of subclinical hypothyroidism was 18 %, primary hypothyroidism was 10 %, clinical hyperthyroidism 16 %.and 64 are in euthyroid state. Conclusion: Thyroid Hormone testing is usually neglected in Type 2 Diabetes mellitus. Unidentified Thyroid Dysfunction will have impact on microvascular and macrovascular complications of Type 2DM. Thus, Routine Screening of Thyroid is advised in all patients of type 2 DM to reduce the morbidity and mortality.
Abstract (English)
Introduction: The co-existence of thyroid dysfunction in type 2 diabetes mellitus patients will worsen the macrovascular and microvascular complications, morbidity, mortality, and quality of life. Over the years it has been evident that there exists regards a strong relationship between thyroid and diabetes. The incidence of thyroid diseases differs in different diabetic population. Thyroid through its hormones exert a great influence on various organs in the body. Similarly insulin also plays a major role in various cellular metabolic activities. Hence, a deficiency or excess of the thyroid hormones are thought to alter the functional integrity of insulin. Aim and Objective: The objective of this study was to determine the prevalence of thyroid dysfunction among patients with Type 2 diabetes. Methods: This Hospital based prospective cross sectional study was conducted from May 2022- May 2023. A total of 100 patients with type-2 diabetes who regularly attend the outpatient Endocrinology Department, GGH Ananthapuramu. A detailed history and examination was done after getting informed consent. Blood samples were collected and sent to the laboratory for the evaluation of thyroid profile. Results: Thyroid dysfunction was found in 36%of the patients with Type 2 DM. Among 100 patients the prevalence of subclinical hypothyroidism was 18 %, primary hypothyroidism was 10 %, clinical hyperthyroidism 16 %.and 64 are in euthyroid state. Conclusion: Thyroid Hormone testing is usually neglected in Type 2 Diabetes mellitus. Unidentified Thyroid Dysfunction will have impact on microvascular and macrovascular complications of Type 2DM. Thus, Routine Screening of Thyroid is advised in all patients of type 2 DM to reduce the morbidity and mortality.
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IJTPR,Vol13,Issue8,Article20.pdf
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Additional details
Dates
- Accepted
-
2023-08-10
Software
References
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