Clinical Study of Extra-Articular Manifestations of Rheumatoid Arthritis
Authors/Creators
- 1. Senior Resident, Department of General Medicine, Goverment Medical College & Hospital, Chatrapati Sambhajinagar, Maharashtra, India
- 2. Assistant Professor, Department of General Medicine, Goverment Medical College & Hospital, Chatrapati Sambhajinagar, Maharashtra, India
- 3. Associate Professor, Department of General Medicine, Goverment Medical College & Hospital, Chatrapati Sambhajinagar, Maharashtra, India
Description
Background: Extra-articular manifestations of rheumatoid arthritis (ExRA) occur in about 40% of patients, either in the beginning or during the course of their disease. The presence of ExRA is associated with severe active disease and increased mortality compared to the general population. So present was carried out to identify the extra-articular manifestations of rheumatoid arthritis and its associated risk factors. Material and Methods: Present study was single-center, prospective Cross-sectional study, conducted in Department of Medicine, MGM Medical College & Hospital Ch. Smabhajinagar, Maharashtra, India during July 2020 to December 2022 were studied. All the diagnosed cases presenting with Rheumatoid arthritis were enrolled in present study. Data analysis was done using Statistical Package for Social Sciences version 20th. Results: In present study 50 patients diagnosed who had Rheumatoid arthritis after applying exclusion criteria were studied. Majority cases, i.e. 56% cases of age group more than 60 years. 80% affected cases being female, while only 20% affected cases being males. 78% cases that had Positive Rheumatoid Factor had these manifestations. Pulmonary manifestations of Rheumatoid Arthritis were 36.4% had interstitial lung disease, 27.3% had Pleural effusion. Conclusion: Present Study concludes that Rheumatoid Arthritis is a serious condition, and extra-articular being a serious complication leading to disability and hampering the daily activity. Thus these patients with extra-articular manifestations should be diagnosed earlier and treated earlier and avoid further complication. Extra-articular manifestations in RA were present in a substantial proportion of patients, which lead to a worse disease outcome. Cardiac, pulmonary, hematological etc systems are affected due to RA factor. They need to be diagnosed early and managed promptly.
Abstract (English)
Background: Extra-articular manifestations of rheumatoid arthritis (ExRA) occur in about 40% of patients, either in the beginning or during the course of their disease. The presence of ExRA is associated with severe active disease and increased mortality compared to the general population. So present was carried out to identify the extra-articular manifestations of rheumatoid arthritis and its associated risk factors. Material and Methods: Present study was single-center, prospective Cross-sectional study, conducted in Department of Medicine, MGM Medical College & Hospital Ch. Smabhajinagar, Maharashtra, India during July 2020 to December 2022 were studied. All the diagnosed cases presenting with Rheumatoid arthritis were enrolled in present study. Data analysis was done using Statistical Package for Social Sciences version 20th. Results: In present study 50 patients diagnosed who had Rheumatoid arthritis after applying exclusion criteria were studied. Majority cases, i.e. 56% cases of age group more than 60 years. 80% affected cases being female, while only 20% affected cases being males. 78% cases that had Positive Rheumatoid Factor had these manifestations. Pulmonary manifestations of Rheumatoid Arthritis were 36.4% had interstitial lung disease, 27.3% had Pleural effusion. Conclusion: Present Study concludes that Rheumatoid Arthritis is a serious condition, and extra-articular being a serious complication leading to disability and hampering the daily activity. Thus these patients with extra-articular manifestations should be diagnosed earlier and treated earlier and avoid further complication. Extra-articular manifestations in RA were present in a substantial proportion of patients, which lead to a worse disease outcome. Cardiac, pulmonary, hematological etc systems are affected due to RA factor. They need to be diagnosed early and managed promptly.
Files
IJPCR,Vol16,Issue2,Article296.pdf
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Additional details
Dates
- Accepted
-
2024-01-26
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue2,Article296.pdf
- Development Status
- Active
References
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