Correlation of Atherogenic Index of Plasma with Coronary Artery Disease in Myocardial Infarction Patients: An Observational Study from NorthIndia
Authors/Creators
- 1. Senior Resident, Department of Cardiology, SMS Medical College, Jaipur
- 2. Assistant Professor, Department of Cardiology, SMS Medical College, Jaipur
Description
Background: Atherogenic Index of Plasma (AIP) is a newer marker of dyslipidemia that includes both atherogenic and anti-atherogenic lipid factors, i.e. triglycerides and high-density lipoprotein, and is recently studied for various cardio-vascular disease risk evaluations. However, its correlation with coronary artery disease (CAD) is scarcely described in the current literature. Aim: To study the correlation of AIP with CAD in myocardial infarction (MI) patients. Material and Methods: This was a single-centered observational study for a period of six months. Patients of age ≥18 years with a diagnosis of acute MI were included in this study, and lipid analysis was performed to identify the AIP. Then the patients underwent conventional CAG, and the GENSINI severity score was calculated on the basis of angiographic results. Both of these parameters were then correlated with Pearson’s ‘r’ correlation analysis and, a p-value <0.05 was considered statistically significant. Results: A total of 114 patients fulfilled the eligibility criteria and were included in this study. The mean age of the study group was 60.7 years, and male participants were more in numbers than female individuals (88 vs. 26). The average AIP and GENSINI scores were 0.15 and 35.8 respectively, and correlation analysis between the two parameters demonstrated a positive r-value (0.4405) with a statistically significant p-value. Conclusion: The study concluded that AIP has a positive correlation with CAD severity in the MI population.
Abstract (English)
Background: Atherogenic Index of Plasma (AIP) is a newer marker of dyslipidemia that includes both atherogenic and anti-atherogenic lipid factors, i.e. triglycerides and high-density lipoprotein, and is recently studied for various cardio-vascular disease risk evaluations. However, its correlation with coronary artery disease (CAD) is scarcely described in the current literature. Aim: To study the correlation of AIP with CAD in myocardial infarction (MI) patients. Material and Methods: This was a single-centered observational study for a period of six months. Patients of age ≥18 years with a diagnosis of acute MI were included in this study, and lipid analysis was performed to identify the AIP. Then the patients underwent conventional CAG, and the GENSINI severity score was calculated on the basis of angiographic results. Both of these parameters were then correlated with Pearson’s ‘r’ correlation analysis and, a p-value <0.05 was considered statistically significant. Results: A total of 114 patients fulfilled the eligibility criteria and were included in this study. The mean age of the study group was 60.7 years, and male participants were more in numbers than female individuals (88 vs. 26). The average AIP and GENSINI scores were 0.15 and 35.8 respectively, and correlation analysis between the two parameters demonstrated a positive r-value (0.4405) with a statistically significant p-value. Conclusion: The study concluded that AIP has a positive correlation with CAD severity in the MI population.
Files
IJPCR,Vol16,Issue2,Article212.pdf
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Additional details
Dates
- Accepted
-
2024-01-18
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue2,Article212.pdf
- Development Status
- Active
References
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