To Study the Role of Serum Lactate Dehydrogenase in Prediction of Adverse Outcomes of Pre-Eclampsia and Eclampsia
Authors/Creators
- 1. Assistant Professor, Department of Obstetrics and Gynaecology, TMMC and RC, Moradabad, UP
- 2. Professor, Department of Obstetrics and Gynaecology, TMMC and RC, Moradabad, UP
Description
Background: In developing nations, pregnancy-induced hypertension is one of the most dreaded complications. This study aims to assess the relationship between blood LDH levels and the incidence, risk factors, and consequences of pre-eclampsia and eclampsia. The purpose of this research is to determine if serum lactate dehydrogenase plays a part in predicting the unfavorable consequences of pre-eclampsia and eclampsia. Methods: From October 2021 to September 2023, the present retrospective study was conducted at Department of Obstetrics and Gynecology, TMMC and RC, Moradabad, Uttar Pradesh. The patients were chosen from the labor room register admissions from the previous few years, regardless of age or parity, as well as from patients who were admitted as emergency cases. The patient details, including the whole obstetric history, examination, and laboratory results, were examined on a proforma created especially for this study. Results: 76% of the preeclampsia and 96% of the eclampsia patients in the study were unbooked cases, and the majority of them lived in rural areas, with the remainder patients coming from urban slums. Small proportions of patients with pre-eclampsia and eclampsia have hyperbilirubinemia. There was also evidence of abnormal liver enzyme levels in a small subset of pre-eclamptic and eclamptic patients. More than 600 IU/L of LDH was shown to be significantly higher in pre-eclamptic and eclamptic patients. Conclusion: Significant maternal and neonatal morbidity and mortality are linked to eclampsia. Due to a high percentage of unbooked patients and the majority not receiving therapeutic intervention prior to admission, there is a greater fatality rate. 76% of the preeclampsia and 96% of the eclampsia patients in the study were unbooked cases, and the majority of them lived in rural areas, with the remainder patients coming from urban slums. Small proportions of patients with pre-eclampsia and eclampsia have hyperbilirubinemia. There was also evidence of abnormal liver enzyme levels in a small subset of pre-eclamptic and eclamptic patients. More than 600 IU/L of LDH was shown to be significantly greater in pre-eclamptic and eclamptic patients.
Abstract (English)
Background: In developing nations, pregnancy-induced hypertension is one of the most dreaded complications. This study aims to assess the relationship between blood LDH levels and the incidence, risk factors, and consequences of pre-eclampsia and eclampsia. The purpose of this research is to determine if serum lactate dehydrogenase plays a part in predicting the unfavorable consequences of pre-eclampsia and eclampsia. Methods: From October 2021 to September 2023, the present retrospective study was conducted at Department of Obstetrics and Gynecology, TMMC and RC, Moradabad, Uttar Pradesh. The patients were chosen from the labor room register admissions from the previous few years, regardless of age or parity, as well as from patients who were admitted as emergency cases. The patient details, including the whole obstetric history, examination, and laboratory results, were examined on a proforma created especially for this study. Results: 76% of the preeclampsia and 96% of the eclampsia patients in the study were unbooked cases, and the majority of them lived in rural areas, with the remainder patients coming from urban slums. Small proportions of patients with pre-eclampsia and eclampsia have hyperbilirubinemia. There was also evidence of abnormal liver enzyme levels in a small subset of pre-eclamptic and eclamptic patients. More than 600 IU/L of LDH was shown to be significantly higher in pre-eclamptic and eclamptic patients. Conclusion: Significant maternal and neonatal morbidity and mortality are linked to eclampsia. Due to a high percentage of unbooked patients and the majority not receiving therapeutic intervention prior to admission, there is a greater fatality rate. 76% of the preeclampsia and 96% of the eclampsia patients in the study were unbooked cases, and the majority of them lived in rural areas, with the remainder patients coming from urban slums. Small proportions of patients with pre-eclampsia and eclampsia have hyperbilirubinemia. There was also evidence of abnormal liver enzyme levels in a small subset of pre-eclamptic and eclamptic patients. More than 600 IU/L of LDH was shown to be significantly greater in pre-eclamptic and eclamptic patients.
Files
IJPCR,Vol16,Issue2,Article173.pdf
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Additional details
Dates
- Accepted
-
2024-02-22
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue2,Article173.pdf
- Development Status
- Active
References
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