NANOCAPSULES: A NOVEL DRUG DELIVERY SYSTEM

Nano capsules are vesicular system in which the drug is confined to a cavity consisting of an inner liquid core surrounding by a polymeric membrane. Nano capsule is a Nanoparticle that is spherical, hollow structure with a diameter less than 200nm in which desired substance may be placed. They can be filled with a solvent, either polar or non- polar. Nano capsules can be different from other Nanoparticles because they have well defined core and shell, whereas the latter do not. When it is made from polymers, Nano capsules can be referred as hollow polymer nanostructures. Polymers are large molecules composed of repeating chemical units. The smallest repeating unit is called a mer. The better distribution of bioactive compounds via targeted delivery via nano capsules presents various problems and potential for future study and development of novel improved therapeutics. They can be used in the delivery of active pharmaceutical ingredients. They provide the novel effective drug delivery systems in the upcoming future.   The main goal of this review was to describe preparation techniques available for production of polymeric nanoparticles. The drug loaded nanosphere / nano capsules now can be produced by simple, safe, and reproductive technique available. Nano capsules are a contribution to the methodological development for formulation by various methods, mainly the interfacial polymerization and interfacial nano deposition.

Keywords: Nanocapsules, Polymers, Nanoparticles, Drug, Polymerization.