MR1-restricted T-cell clonotypes are associated with 'resistance' to Mycobacterium Tuberculosis infection - TRA/D immunoSEQ
Description
Summary
- Number of files: 39
- Data format: tsv
- Data type: TCRA/D immunoSEQ (Adaptive Biotechnologies)
- immunoSEQ version: v2
- Sample type: peripheral blood mononuclear cells (PBMCs)
- Genomic DNA extraction protocol: QIAGEN DNeasy Blood and Tissue kit
Sample description
Peripheral blood samples were collected from participants enrolled in a longitudinal cohort study based in Uganda. Donors were classified as either "resistors" (RSTRs, n = 19, defined as concordantly negative for tuberculin skin test and IFNg release assay despite high environmental exposure) or latently infected with M. Tuberculosis (LTBI, n = 20, concordantly as longitudinally positive for tuberculin skin test and IFNg release assay). Genomic DNA (gDNA) was extracted from cryopreserved PBMCs without stimulation or enrichment of T-cells using the Quiagen DNeasy Blood and Tissue kit. Protocol can be found at: https://www.qiagen.com/us/products/discovery-and-translational-research/dna-rna-purification/dna-purification/genomic-dna/dneasy-blood-and-tissue-kit
Files
Files
(4.0 GB)
| Name | Size | Download all |
|---|---|---|
|
md5:0ed29b8e1fc02454749244e11a82be7b
|
171.0 MB | Download |
|
md5:c4bb75b5b627c25b0a41300ed22d41cc
|
53.9 MB | Download |
|
md5:fe3ddda19fe1888922c93f855cc2c665
|
138.3 MB | Download |
|
md5:1fab692ec62057485fa357f29c3db9db
|
155.8 MB | Download |
|
md5:c9eabf3847e76d5d32ce9534572e026c
|
137.6 MB | Download |
|
md5:41fab8bf4a813fdc95c5864edbfeb302
|
27.1 MB | Download |
|
md5:bc15aab8f62323391dc68581eb3a378d
|
80.6 MB | Download |
|
md5:8822b168e1d62b3f7bd72520abcb6769
|
80.9 MB | Download |
|
md5:db63884427399f0301467858d192bd8a
|
87.0 MB | Download |
|
md5:32aff36f7c7b40b897b3a80cf46fe247
|
80.4 MB | Download |
|
md5:bd5129ef6906b8396ba2e26b4160df12
|
145.8 MB | Download |
|
md5:7f4c1a242f5695fbc42b4ab63a9d4664
|
76.2 MB | Download |
|
md5:1d1ab7709b60c85f64714d3a96a5af0c
|
136.8 MB | Download |
|
md5:0afa82839764bf10107f95e32f573723
|
90.6 MB | Download |
|
md5:7661c0b8efcd50e613da443d311bcbe1
|
97.5 MB | Download |
|
md5:7370ff2058655cf08a2936e3f01b11d1
|
54.3 MB | Download |
|
md5:160c60b4866f3644b42761bd52b1ac37
|
108.1 MB | Download |
|
md5:aa4772f38333094c218a351a1b862c02
|
55.2 MB | Download |
|
md5:c7d1c7d5ba9feb5bdbc45268bc0c6854
|
109.5 MB | Download |
|
md5:b2ac742681ab4523d91bfa9aa0681910
|
159.4 MB | Download |
|
md5:83f271de220c696c37b1fdf412e6cb00
|
59.3 MB | Download |
|
md5:7cab04499e085cbdd21afabeb028383a
|
97.8 MB | Download |
|
md5:2c0a8f87e912797ba9d1b6d2322c5f5c
|
105.8 MB | Download |
|
md5:09d3ad5525fa5e21cf540ac4b8140194
|
33.1 MB | Download |
|
md5:6dea8298eb95bf23ad000a67fc6fc8c6
|
155.5 MB | Download |
|
md5:f1e762cca6a690b4fffbdec5304d5b71
|
87.8 MB | Download |
|
md5:fc97688aae22d2bf0693b91a17c7b3f2
|
38.9 MB | Download |
|
md5:d5785082e57efcf6d5ceabb234744fff
|
34.2 MB | Download |
|
md5:62122c2eea325f08687525f378b61de0
|
109.9 MB | Download |
|
md5:8498072199e9140d3d074663da71fceb
|
78.4 MB | Download |
|
md5:4f748f2e59e00cef9be5a7f224ba68ee
|
117.7 MB | Download |
|
md5:e4e421d0f94190941a1518e6f72daa80
|
181.5 MB | Download |
|
md5:e64b91f861c7ac8a1f0cf200cc11b9cd
|
136.8 MB | Download |
|
md5:fd3106e565d8520f16c5c05e7080f8c6
|
142.9 MB | Download |
|
md5:e3fa9aa51e6e3b1f4b63e0fb83b1fffe
|
141.0 MB | Download |
|
md5:c80524c2c93787319546219dcd3b1c9d
|
79.9 MB | Download |
|
md5:c9c2e44eecc7e7f5bca69da789a21301
|
130.0 MB | Download |
|
md5:3dbef42ce0721fd14b97e973b1560c26
|
133.6 MB | Download |
|
md5:ca0f02f5ee979dcd499776bdbf906c41
|
116.3 MB | Download |