Calculator for determining directional Earth Movers Distance between distributions in .txt files from mass cytometric analysis
Description
Earth Movers Distance (aka Wasserstein distance) is a way of describing the difference between two distributions. It is a more accurate way of demonstrating differences in cytometric datasets than metrics such as delta-MFI, which neglect the single-cell nature of these datasets.
This version of the code is aimed at mass cytometric datasets, so includes an arcsinh transformation.
EMD is a non-directional measurement of difference, so the directionality is added by comparing the means of the datasets. This can be changed to median or another metric if needed.
Files
EMD_comprision_directional_tool.ipynb
Files
(10.6 kB)
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md5:9a6349552ab6c1cb9592ce2c265b76e3
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Additional details
Funding
- NIHR Academy
- NIHR Academic Clinical Lectureship CL-2019-18-007