Published April 17, 2024 | Version v1

PITUITARY STONE ADENOMA ASSOCIATED WITH SEVERE HYPERPROLACTINEMIA CASE REPORT

  • 1. Endocrinology and Diabetology Department, Mohammed V Military Academic Hospital, Faculty of Medicine and Pharmacy, Mohammed V- UniversitySouissi, Rabat, Morocco.
  • 2. Neurosurgery Department, Mohammed V Military Academic Hospital, Faculty of Medicine and Pharmacy, Mohammed V- UniversitySouissi, Rabat, Morocco.

Description

A 35-year-old patient consulting for erectile dysfunction, with a progressive visual acuity loss. Biological assessment revealed hyperprolactinemia at 4315 ng/ml and low testosteronemia at 6.8 nmol/l. Skull X-ray showed an enlarged sellaturcica with voluminous intra- and suprasellar calcifications. A cranial CT scan revealed an intra- and suprasellar calcified mass. Transphenoidal surgery was performed. The tumor was partially removed and the piece was made of calcified grayish granular tissue. Histological examination showed adenomatous cells with large granular calcification lesions. Immunohistochemistry confirmed prolactin adenoma. Cabergoline treatment was effective on the calcified tissue remaining after surgery.

 

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