A Review On The Effect Of Anxiety In Rat Using Hole Board Apparatus

Anxiety disorders are biosocial conditions that involve systemic or situational responses to perceived threats. Childhood anxiety affects one in four children between the ages of 13 and 18. The average age of onset is 11 years. Overall prevalence in children under 18 years of age ranges from 5.7% to 12.8%. Anxiety disorders are usually treated with medication, some form of psychotherapy, or both. The main medications used for anxiety disorders are antidepressants, anxiolytics, and beta blockers to control physical symptoms. Behavioral studies in animal subjects (mice) are important to understand this disease and introduce new treatments from a translational perspective. The Hole-board apparatus has emerged as a widely used test for studying anxiety-related behavior in relationships. We focused on the Hall apparatus as an advanced tool to measure research activity in laboratory mice. Other behavioral control mechanisms (eg, emotional responses, risk assessment, active coping) may play an additional role in shaping the animal's activity on the Hole-board apparatus.