NSAID Induced Acute Kidney Injury (AKI): A Case Study

Acute Kidney Injury, previously known as Acute Renal Failure, denotes a sudden and often reversible reduction in the kidney function, measured by increased creatinine or decreased urine volume. Although immediately after a renal insult, blood urea nitrogen or creatinine levels may be within the normal range, the only sign of Acute Kidney Injury may be a decline in the urine output. Acute Kidney Injury can lead to the accumulation of water, sodium, and other metabolic products. The crude odds ratio for Kidney Injury in non-steroidal anti-inflammatory drug users compared to non-users ranged from 1.12-5.25 and was greater than 1. Renal cell damage is more prominent in patients taking non-steroidal anti-inflammatory drugs. The major etiological factors contributing to Acute Kidney Injury are infections, drug induction, obstructive uropathy, dehydration, snake bite, cardio renal syndrome. The current case report features a patient who was admitted to the Gastroenterology department from outpatient basis due to an elevation in her serum creatinine level (4.7 mg/dL).