Quantitative results of the analysis of novel ossicle particles used in mandible bone regeneration
Contributors
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1.
Universidad de Granada
- 2. ibs.GRANADA
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3.
Hospital General Universitario Gregorio Marañón
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4.
Hospital Universitario Virgen de las Nieves
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5.
Universidad Nacional de Córdoba
Description
Dataset corresponding to the results of the characterization analysis of novel holothurian ossicle biomaterials. These biomaterials were evaluated at three levels:
1) Ex vivo analysis to determine thr potential cytotoxic effects of these biomaterials on human fibroblasts using LIVE/DEAD and quantification of DNA released to the medium.
2) In vivo analysis to determine the potential systemic effects of these biomaterials grafted subcutaneously in laboratory rats.
3) Histochemical and immunohistochemical analysis to determine the potential effects of these biomaterials on mandible bone regeneration.
These results correspond to the publication entitled "EVALUATION OF HOLOTHURIAN OSSICLES AS A BIOLOGICAL BIOMATERIAL FOR MANDIBULAR BONE REGENERATION".
Files
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Additional details
Related works
- Is source of
- Dataset: 10.22203/eCM.v049a01 (DOI)
References
- Ortiz-Arrabal O, Bullejos-Martínez E, Chato-Astrain J, Carriel V, Martínez-Plaza A, Martín-Piedra MA, Garzón I, Fernandez-Valades R, España-López A, Rodríguez IÁ, Alaminos M. Evaluation of holothurian ossicles as a biological biomaterial for mandibular bone regeneration. Eur Cell Mater. 2025;49:1-16. doi: 10.22203/eCM.v049a01