World Academy of Science, Engineering and Technology
Published December 20, 2009 | Version 9437
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Skin Lesion Segmentation Using Color Channel Optimization and Clustering-based Histogram Thresholding

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Automatic segmentation of skin lesions is the first step towards the automated analysis of malignant melanoma. Although numerous segmentation methods have been developed, few studies have focused on determining the most effective color space for melanoma application. This paper proposes an automatic segmentation algorithm based on color space analysis and clustering-based histogram thresholding, a process which is able to determine the optimal color channel for detecting the borders in dermoscopy images. The algorithm is tested on a set of 30 high resolution dermoscopy images. A comprehensive evaluation of the results is provided, where borders manually drawn by four dermatologists, are compared to automated borders detected by the proposed algorithm, applying three previously used metrics of accuracy, sensitivity, and specificity and a new metric of similarity. By performing ROC analysis and ranking the metrics, it is demonstrated that the best results are obtained with the X and XoYoR color channels, resulting in an accuracy of approximately 97%. The proposed method is also compared with two state-of-theart skin lesion segmentation methods.

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References

  • G. Argenziano, H. P. Soyer, S. Chimenti, and R. T. et al., "Dermoscopy of pigmented skin lesions: Results of a consensus meeting via the Internet," Journal of the American Academy of Dermatology, vol. 48, pp. 679-693, 2003.
  • P. Braun, H. Rabinovitz, M. Oliviero, A. Kopf, and J. Saurat, "Dermoscopy of pigmented lesions," Journal of the American Academy of Dermatology, vol. 52, no. 1, pp. 109-121, 2005.
  • A. Perrinaud, O. Gaide, L. French, J.-H. Saurat, A. Marghoob, and R. Braun, "Can automated dermoscopy image analysis instruments provide added benefit for the dermatologist? A study comparing the results of three systems," British Journal of Dermatology, vol. 157, pp. 926-933, 2007.
  • M. E. Celebi, H. Iyatomi, G. Schaefer, and W. V. Stoecker, "Lesion border detection in dermoscopy images," Computerized Medical Imaging and Graphics, vol. 33, no. 2, pp. 148-153, 2009.
  • H. Iyatomi, H. Oka, M. E. Celebi, M. Hashimoto, M. Hagiwara, M. Tanaka, and K. Ogawa, "An improved internet-based melanoma screening system with dermatologist-like tumor area extraction algorithm," Computerized Medical Imaging and Graphics, vol. 32, no. 7, pp. 566-579, 2008.
  • M. Hintz-Madsen, L. K. Hansen, J. Larsen, and K. T. Drzewiecki, "A probabilistic neural network framework for the detection of malignant melanoma." Artificial neural networks in cancer diagnosis. Prognosis and Patient Management, pp. 141-183, 2001.
  • R. Melli, C. Grana, and R. Cucchiara, "Comparison of color clustering algorithms for segmentation of dermatological images," in SPIE Medical Imaging, vol. 6144, 2006, pp. 3S1-3S9.
  • G. Hance, S. Umbaugh, R. Moss, and W. V. Stoecker, "Unsupervised color image segmentation:With application to skin tumor borders," IEEE Engineering in Medicine and Biology Magazine, vol. 15, pp. 104-111, 1996.
  • P. Schmid, "Segmentation of digitized dermatoscopic images by twodimensional color clustering," IEEE Transactions on Medical Imaging, vol. 18, no. 2, pp. 164-171, 1999. [10] M. E. Celebi, Y. A. Aslandogan, W. V. Stoecker, H. Iyatomi, H. Oka, and X. Chen, "Unsupervised border detection in dermoscopy images," Skin Research and Technology, vol. 13, pp. 454-462, 2007. [11] M. E. Celebi, H. A. Kingravi, H. Iyatomi, Y. A. Aslandogan, W. V. Stoecker, R. H. Moss, J. M. Malters, J. M. Grichnik, A. A. Marghoob, H. S. Rabinovitz, and S. W. Menzies, "Border detection in dermoscopy images using statistical region merging," Skin Research and Technology, vol. 14, pp. 347-353, 2008. [12] T. Lee, , V. Ng, R. Gallagher, A. Coldman, and D. McLean, "Dullrazor: A software approach to hair removal from images," Computers in Biology and Medicine, vol. 27, pp. 533-543, 1997. [13] L. Lucchese and S. Mitra, "Color image segmentation: A state-of-theart survey," in Proceedings of Indian National Science Academy Part A, PINSA2001, 2001, pp. 207-221. [14] K. N. Plataniotis and A. N. Venetsanopoulos, Color Image Processing and Applications. Springer, 2000. [15] N. Otsu, "A threshold selection method from gray-level histograms," IEEE Transactions on Systems, Man, and Cybernetics, vol. 9, no. 1, pp. 62-66, 1979. [16] R. M. Haralick and L. G. Shapiro, Computer and Robot Vision. Addison-Wesley, 1992, vol. 1. [17] M. E. Celebi, G. Schaefer, H. Iyatomi, W. V. Stoecker, J. M. Malters, and J. M. Grichnik, "An improved objective evaluation measure for border detection in dermoscopy images," to appear in Skin Research and Technology. [18] T. Sorensen, "A method of establishing groups of equal amplitude in plant sociology based on similarity of species and its application to analyses of the vegetation on danish commons." Royal Danish Academy of Sciences and Letters, vol. 5, pp. 1-34, 1948. [19] J. Davis and M. Goadrich, "The relationship between precision-recall and roc curves," in Proceeding of 23rd International Conference on Machine Learning (ICML), vol. 148, 2006, pp. 233-240.