Figure 4 from: Al-Ghamdi AH, Mohamed MZ, Elbadry RM, Fouad AA (2024) Kidney protective effect of sitagliptin in 5-fluorouracil-challenged rats. Pharmacia 71: 1-5. https://doi.org/10.3897/pharmacia.71.e114441

Figure 4 H&E (200×) of rat kidneys from: A. control showing normal renal histology; B, C. 5-fluorouracil (5-FU) group demonstrating marked distortion of kidney architecture, renal tubular necrosis and dilatation, desquamation of lining epithelium (black arrows), interstitial edema, areas of coagulative necrosis (white arrow), and inflammatory cell infiltration (black head); D, E. sitagliptin (SIT 5 mg/kg) + 5-FU and (SIT 10 mg/kg) + 5-FU, respectively, showing preservation of the normal kidney architecture; F. tubular injury score. *p < 0.05 vs. control, ≠p < 0.05 vs. 5FU. Results are mean ± S.E.M., n = 8, in each group.