Published February 28, 2024
| Version v2
Journal article
Open
Genome-sequence analyses identify novel risk loci for multiple system atrophy
Authors/Creators
- 1. Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA
- 2. Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA
Description
This repository contains code used in -
- Data quality check and pre-GWAS prep
- Genome-wide association studies (Additive and Recessive models), and regional plots
- Rare variant analysis
- Transcriptome-wide association studies
- Leave-one-out analysis and conditional analysis for validation
- Pathway enrichment and repeat expansion analysis
presented in the article "Genome-sequence analyses identify novel risk loci for multiple system atrophy".
Files
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(82.0 MB)
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