A REVIEW ON PILOT PLANT SCALE UP TECHNIQUES AND PLATFORM TECHNOLOGY

In modern context, as per market demand there is surely an augmentation or decrease in production, this is called SUPAC. Distinct recommendations are made for those diverse sorts of SUPAC in by various regulating organizations for manufacture of items. Here SUPAC guidelines and post approval adjustments are provided for production in this review study. determined that SUPAC guideline line offer benefits as: This Review Focus on Reduced processing period for site transfers, saving operational overhead & maintenance expenditures. More quicker deployment of equipment and method improvements, better yield & Reduce failure investigations. More quicker adoption, increase in lot sizes and Manufacture of fewer un commercial stability batches and Reducing stability testing/costs.

Keywords : Pilot plant techniques ,solid dosage form, tablet compression, SUPAC, Post approval changes, Lot size , Site Transfer, Stability.