TRANSCENDING BARRIERS: INNOVATIONS IN TRANSDERMAL DRUG DELIVERY SYSTEM DESIGN AND THEIR EVALUATION

Traditional needle injections have been replaced by a variety of non-intrusive administrations in recent times. Among these, a transdermal delivery system for drugs (TDDS) offers the most pleasant procedure due to its low rate of refusal, remarkable ease of administration, and exceptional patient amenities and attentiveness. The main benefits of TDDS are reduced side effects, enhanced bioavailability with regulated drug release, and bypass first-pass metabolism. The transdermal system for drug delivery, skin anatomy and physiology, formulation development, and a critical analysis of the particular benefits and drawbacks, preparation, assessment, and application methods, as well as future innovations and limitations for transdermal patch selection, are all succinctly summarised in this review article.