Published February 5, 2024 | Version v3
Dataset Open

Community Package Lasry Dataset

  • 1. ROR icon Ludwig-Maximilians-Universität München
  • 2. ROR icon Helmholtz Zentrum München

Contributors

Project leader:

  • 1. ROR icon Ludwig-Maximilians-Universität München
  • 2. ROR icon Helmholtz Zentrum München

Description

The Community package (https://github.com/SoloveyMaria/community) is an R package designed for the analysis of single-cell RNA sequencing data, specifically for inferring interactions between different cell types. The dataset provided here is compatible with the Community tool, allowing for direct utilization. 

The dataset associated with this research has undergone peer review and has been published in the journal Nature Cancer. The publication can be accessed via the following link: https://doi.org/10.1038/s43018-022-00480-0. For access to the raw data, please visit: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE185381. It's important to note that the data in this repository has undergone batch correction and normalization, and the corresponding metadata has been appropriately adjusted. This processed data serves as the input for the Community tool.

Files

anno_cells_norm.txt

Files (734.1 MB)

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md5:7c53f04455dcf645adc8a96fb2017482
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Additional details

References

  • Lasry, A., et al. (2023). An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia. Nature cancer