RESEALED ERYTHROCYTES: A NOVEL APPROACH TO TREAT CHRONIC DISEASES

In this area of pharmaceutical innovation, there are more than 30 different drug delivery systems. As people become more interested in consuming safe medications that can be delivered to the intended target spot with few adverse effects, the current environment is concentrating more on targeted drug delivery systems. In actuality, the bio-distribution of medications throughout the body is essentially the fundamental issue with systemic drug delivery. An innovative drug administration method using resealed erythrocytes is now required to solve this issue and increase patient compliance and efficiency. Blood is drawn from the target organism, and erythrocytes and plasma are separated to create carrier erythrocytes. The cells are broken up in a few different ways, the erythrocytes are then hooked up to the drug, they are then resealed, and the resulting carriers are referred to as "resealed erythrocytes". The negative effects of numerous medications, including aspirin, steroids, and cancer treatments, are reduced by resealing erythrocytes. Because they can circulate throughout the entire body and are biocompatible, sealed erythrocytes are becoming more and more important. They also exhibit zero order release kinetics, complete biodegradability, lack of hazardous product, predictable life span, and lowering drug side effects. And these play a big role in treating chronic illnesses like drug addiction, cancer, diabetes mellitus, rheumatoid arthritis, and HIV infection.

Keywords: Resealed Erythrocytes, Erythrocytes, Erythrosomes, Red Blood Cells, Drug Carriers.