Published January 24, 2024
| Version v1
Dataset
Open
Alterations in Zonal Distribution and Plasma Membrane Localization of Hepatocyte Bile Acid Transporters in NAFLD Patients
Authors/Creators
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1.
University of North Carolina at Chapel Hill
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2.
Duke Medical Center
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3.
Auburn University
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4.
Duke University
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5.
Mayo Clinic
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6.
University of Helsinki
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7.
Simcyp (United Kingdom)
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8.
University of Eastern Finland
Description
This dataset includes R code and the accompanying Microsoft Excel raw data files used for data analysis and Bayesian modeling of the zonal abundance, plasma membrane localization, and membrane-localized zonal abundance phenotypes reported in "Alterations in Zonal Distribution and Plasma Membrane Localization of Hepatocyte Bile Acid Transporters in NAFLD Patients" (published in Hepatology Communications, 2024). Raw data and R code files used to evaluate the hepatic acinus size phenotype as reported in the Supplement Digital Content of this publication are also included with this upload. Please reference the following document for more detailed information: Murphyetal_DataRepositoryGuide.docx.
Files
Bayes Models_ExcelFiles.zip
Files
(72.0 MB)
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Additional details
Funding
- Simcyp (United Kingdom)
- Certara Simcyp Grant and Partnership Scheme 2020/2021
- Duke Medical Center
- Duke NAFLD Clinical-Translational Research Program Discretionary Funding
- University of North Carolina at Chapel Hill
- UNC-Duke Nannerl O. Keohane Distinguished Visiting Professorship N/A
- National Institute of General Medical Sciences
- UNC-Duke Collaborative Clinical Pharmacology T32 Postdoctoral Training Program T32GM086330
- National Institute of General Medical Sciences
- Maximizing Investigators' Research Award (MIRA) R35GM122576
- Research Council of Finland
- Academy of Finland Grant 332660