Published June 11, 2026 | Version v1
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Data and simulation code from: Probability of early infection extinction depends linearly on the virus clearance rate

  • 1. University of Szeged
  • 2. Moffitt Cancer Center
  • 3. Zhejiang University of Science and Technology

Description

We provide an in silico study of stochastic viral infection extinction from a pharmacokinetical viewpoint. Our work considers a non-specific antiviral drug that increases the virus clearance rate, and we investigate the effect of this drug on early infection extinction. Infection extinction data is generated by a hybrid multiscale framework that applies both continuous and discrete mathematical approaches. The central result of our paper is the observation, analysis, and explanation of a linear relationship between the virus clearance rate and the probability of early infection extinction. The derivation behind this simple relationship is given by merging different mathematical toolboxes.

Notes

Funding provided by: National Research, Development and Innovation Office
ROR ID: https://ror.org/03g2am276
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Funding provided by: National Laboratory for Health Security
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