Astragalus membranaceus Bunge
Authors/Creators
- 1. Dipartimento di Farmacia, Università " G. d'Annunzio " of Chieti-Pescara, Via dei Vestini 31, 66100, Chieti Scalo, CH, Italy & Dipartimento di Scienze Farmaceutiche, Università degli Studi di Perugia, Via del Liceo, 06123, Perugia, Italy
- 2. Dipartimento di Farmacia, Università " G. d'Annunzio " of Chieti-Pescara, Via dei Vestini 31, 66100, Chieti Scalo, CH, Italy
Description
5.10.1. Astragalus membranaceus (Fisch.) Bunge
A. membranaceus (huang qi) is a plant described in the Chinese herbal medicine traditions. Its polysaccharide fraction is well known to enforce the immune responses and to exert a marked neurprotective effect (Huang et al., 2017). In 2013 Ji and coworkers (2013b) obtained the Se-P from a root aqueous extract and subsequently tested it as a growth inhibitory agent in vitro against MCF-7 (human breast cancer) in the concentration range from 6.25 μg/mL to 200 μg/mL. The recorded IC 50 value was 14.52 μg/mL and the best inhibitory rate at 24 h, 48 h, and 72 h were 50.0%, 76.2%, and 84.7% respectively. Anyway, authors did not refer about effects of the native polysaccharide and did not use any reference drug.
Notes
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Linked records
Additional details
Identifiers
Biodiversity
- Scientific name authorship
- Bunge
- Kingdom
- Plantae
- Phylum
- Tracheophyta
- Order
- Fabales
- Family
- Fabaceae
- Genus
- Astragalus
- Species
- membranaceus
- Taxon rank
- species
References
- Huang, Y. C., Tsai, H. J., Lu, M. K., Lin, C. H., Yeh, C. W., Liu, H. K., Shiao, Y. J., 2017. Astragalus membranaceus - polysaccharides ameliorates obesity, hepatic steatosis, neuroinflammation and cognition impairment without affecting amyloid deposition in metabolically stressed APPswe / PS 1 dE 9 mice. Int. J. Mol. Sci. 18, 2746.