Published February 20, 2024
| Version 0.0.1
Dataset
Open
European LD files for GhostKnockoffGWAS
Authors/Creators
Description
This contains pre-processed LD files (Sigma matrix, S matrix, ...etc) computed on the EUR cohort of Pan-UKB LD data. It is intended to be used as an input to the GhostKnockoffGWAS pipeline.
- We restricted our attention to the EUR panel
- We filtered the original HailBlockMatrix LD panel to genotypes that are typed (i.e. imputed SNPs were removed)
- Coordinates in both hg19 and hg38 are available. Conversion from hg19 to hg38 were achieved by the R package liftOver.
- Downloading and processing of the original HailBlockMatrix formatted data is accomplished by the EasyLD.jl software: https://biona001.github.io/EasyLD.jl
- Knockoff optimization were carried out by the Knockoffs.jl julia package: https://github.com/biona001/Knockoffs.jl
- The result (i.e. files available in this site) is saved in .csv and .h5 formatted files for easier access, which is directly readable by GhostKnockoffGWAS.
Files
EUR.zip
Files
(7.5 GB)
| Name | Size | Download all |
|---|---|---|
|
md5:803efe4fe269ed64719356e91bd6f457
|
7.5 GB | Preview Download |
Additional details
Dates
- Created
-
2024-02
Software
- Repository URL
- https://github.com/biona001/GhostKnockoffGWAS